Pro-Oxidative Processes and Cytokine Response to Training in Professional Basketball Players

Zembroń-Łacny, Agnieszka; Słowińska-Lisowska, Małgorzata; Superlak, Edward

doi:10.2478/v10078-008-0020-z

Cited by 20 publications

(25 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…7 In addition, the cysteine derivative, GSH, is synthesized in erythrocytes and glutathione disulfide is transported outside the cell to maintain a high GSH/oxidized glutathione (GSSG) ratio. 3,29,30 Disulfide exchange reac-tions occur between protein thiols and low molecular weight disulfides. 3 Recently, Tsakiris et al 26 reported that vitamin E supplementation protected glucose-6-phosphate dehydrogenase activity in intense training.…”

Section: Discussionmentioning

confidence: 99%

Oral vitamin C and E combination modulates blood lipid peroxidation and antioxidant vitamin levels in maximal exercising basketball players

Nazıroğlu

Kılınç

Uğuz

et al. 2010

Cell Biochemistry & Function

View full text Add to dashboard Cite

Oxidative stress occurs during maximal exercise, perhaps as a result of increased consumption of oxygen. Vitamins C and E can overcome the effects of antioxidants in exercise. We investigated the effects of supplementation with a combination of vitamin C and E (VCE) on blood lipid peroxidation (LP) and antioxidant levels following maximal training in basketball players.Blood samples were taken from 14 players (group A) and divided into two subgroups namely maximal training (group B) and maximal training plus VCE groups (group C). Group B maximally exercised for 35 days. VCE was supplemented to group C for 35 days and blood samples were taken from group B and C. Plasma and hemolyzed erythrocyte samples were obtained from the players.Erythrocyte glutathione peroxidase (GSH-Px) activity and plasma vitamin E concentration were lower in group B than in group A, whereas plasma and erythrocyte LP levels were higher in group B than in group A. Plasma vitamin A, vitamin E, erythrocyte GSH-Px, and reduced glutathione (GSH) values were higher in group C than in groups A and B although LP levels in plasma and erythrocytes were lower in group C than in group A and B. beta-Carotene values did not change in the three groups.In conclusion, VCE supplementation in maximal exercising basketball players may strengthen the antioxidant defense system by decreasing reactive oxygen species (ROS).

show abstract

Section: Discussionmentioning

confidence: 99%

Oral vitamin C and E combination modulates blood lipid peroxidation and antioxidant vitamin levels in maximal exercising basketball players

Nazıroğlu

Kılınç

Uğuz

et al. 2010

Cell Biochemistry & Function

View full text Add to dashboard Cite

show abstract

“…TBARS has been used to detect lipid peroxidation in many body fluids and is a well established indirect measure of total oxidative stress (28)(29)(30)(31)(32)(33). A standard curve was generated for each assay run with malondialdehyde (MDA) provided by Cayman Chemical using a concentration range from 0 to 50 mmol/L.…”

Section: Measurement Of Lipid Peroxidationmentioning

confidence: 99%

Supplementation of cryomedium with ascorbic acid–2-glucoside (AA2G) improves human sperm post-thaw motility

Jenkins

Aston

Carrell

2011

Fertility and Sterility

View full text Add to dashboard Cite

“…TBARS assay was performed using a slight adaptation of the reference (Zembron-Lacny et al 2009). Stock solution contained 67 mg of thiobarbituric acid (Sigma-Aldrich) in 1 mL of dimethyl sulfoxide and 9 mL of deionized water.…”

Section: Tbars Assaymentioning

confidence: 99%

Investigation of oxidative stress in blood, brain, kidney, and liver after oxime antidote HI-6 application in a mouse experimental model

Pohanka

Sobotka

Svobodová

et al. 2011

Drug and Chemical Toxicology

View full text Add to dashboard Cite

Oxime reactivator HI-6 (asoxime, in some sources) is a potent antidote suitable for treatment of intoxication by nerve agents. Despite the fact that HI-6 is considered for practical application in emergency situations, the impact of HI-6 on patients' bodies has not been established yet. The present experiment was carried out in order to estimate whether HI-6 would be able to trigger or protect from oxidative stress in a BALB/c mice model. HI-6 was applied in doses ranging from 0.2 to 20% of LD₅₀. Ferric-reducing antioxidant power (FRAP), thiobarbituric acid reactive substances (TBARS), reduced glutathione (GSH), and glutathione reductase (GR) were assayed in the blood, liver, kidney, and brain of treated animals. It was found that HI-6 does not increase GR or TBARS. On the contrary, TBARS levels in the brain and liver were found to be significantly decreased in HI-6-treated animals. Pertinent antioxidant properties of HI-6 were excluded by the FRAP method. Endogenous antioxidants were unchanged, with the exception of the kidney. Low-molecular-weight antioxidants assayed by the FRAP method were significantly decreased in kidneys of animals treated with HI-6. However, GSH partially recovered the loss of the other low-molecular-weight antioxidants and was significantly increased in the kidney of HI-6-exposed mice. HI-6 potential to produce nephropathy is hypothesized. The achieved conclusions were quite surprising and showed a complex impact of HI-6 on the body.

show abstract

Pro-Oxidative Processes and Cytokine Response to Training in Professional Basketball Players

Abstract: In the present study, we evaluated the plasma concentration of inflammatory mediators including cytokines and their relation with oxidative damage markers in training cycles p<0.001) and p<0.001)

Cited by 20 publications

References 24 publications

Oral vitamin C and E combination modulates blood lipid peroxidation and antioxidant vitamin levels in maximal exercising basketball players

Oral vitamin C and E combination modulates blood lipid peroxidation and antioxidant vitamin levels in maximal exercising basketball players

Supplementation of cryomedium with ascorbic acid–2-glucoside (AA2G) improves human sperm post-thaw motility

Investigation of oxidative stress in blood, brain, kidney, and liver after oxime antidote HI-6 application in a mouse experimental model

Contact Info

Product

Resources

About