“…[ 282 ] In recent years, researchers found that medications, and especially host modulators, show great potential in resolving or inhibiting the periodontal inflammatory process, particularly in the early phases of periodontitis combined with non‐surgical periodontal treatment. [ 283 , 284 , 285 , 286 , 287 , 288 , 289 ] These host modulators include statins like atorvastatin, rosuvastatin, and simvastatin, as well as alendronate and metformin. [ 80 , 89 , 92 , 95 , 96 , 98 , 99 , 105 , 290 , 291 , 292 , 293 , 294 , 295 , 296 ] Statins exhibit anti‐inflammatory and immunomodulatory properties while inhibiting osteoclasts and stimulating bone morphogenetic proteins.…”