In selective serial disassembly sequence planning, when the target node (component) is reached, the selective disassembly task is completed and the refurbished component is repaired, reused or remanufactured. Since the efficient utilization of existing resources is necessary, it is crucial to predict disassembly operation times and the condition of joints for recycling, reusing or remanufacturing. The method of estimating the disassembly times of a joint if it is intended for remanufacturing, recycling and reuse is an important and urgent requirement for research development and results. The aim of the paper is to investigate the disassembly system with predicted operation times and the quality of product connections (joints) in order to balance the line smoothness index, to minimize a line time factor, line efficiency and profit and minimize an ex post error. Disassembly times for remanufacturing, recycling and reuse are estimated separately based on the historical data of disassembly times and the quality of joints. The presented estimation method of disassembly operation times increases the reliability and efficiency of elaborated balances of tasks in lines. Underestimated disassembly operation times can be compensated for during the idle points in the successive cycles, provided that the transport operations are performed manually and that travel time determines the cycle time.