The prediction of energy production and structural loads within wind farms is of high interest for wind industries to optimize the wind farm design and control under a variety of atmospheric conditions. However, it is still a key challenge to predict them accurately and efficiently due to the complex interactions between wind turbines and turbulent flows. Nowadays, high-fidelity simulations using Reynolds-Averaged Navier-Stokes (RANS) or Large-Eddy Simulation (LES) coupled with actuator disk or actuator line method are widely developed and used in wind farm analysis, but it still needs a huge computational resource, especially in the application of a commercial wind farm with large number of turbines. In this context, a mid-fidelity simulation tool based on the Dynamics Wake Meandering (DWM) model called FAST.Farm has been developed by National Renewable Energy Laboratory (NREL) in order to tackle this challenge. It allows to capture essential physics at the turbine scale as well as at the farm scale in a computational efficient manner. This study focuses on the calibration of DWM model which is the key to minimize inaccuracies between mid-fidelity and high-fidelity simulations regarding key performance indicators, e.g. thrust and power production. The calibration is made for DTU10MW wind turbine and shows a good improvement in accuracy compared to default parameters. The calibrated DWM model is finally employed to forecast the power generation for two turbines within a reference wind farm. A good improvement on the prediction is also obtained thanks to the calibrated parameters.