The tensile strength of the rocks is one of the effective factors in the rupture of structure foundations and underground spaces, the stability of rocky slopes, and the ability to drill and explode in rocks. This research was conducted to estimate tensile strength using methods such as simple regression (SR), multivariate linear regression (MVLR), support vector regression (SVR) with radial basis kernel function, multilayer feed-forward artificial neural network (MFF-ANN), Gaussian process regression (GPR) using squared exponential kernel (SEK) function, and adaptive neuro-fuzzy inference system (ANFIS) based on Gaussian membership function. For this purpose, petrography, and engineering features of the limestone, sandstone, and argillaceous limestone samples in the south of Iran, were assessed. The results obtained from this study were compared with those of previous research, revealing a strong correlation (R2=0.95 to 1.00) between our findings and the published works. To estimate Brazilian tensile strength (BTS), the index properties including water absorption by weight, point load index (PLI), porosity%, P-wave velocity (Vp), and density were considered as inputs. Methods were compared using various criteria. The SVR precision (R=0.96) was higher than MFF-ANN (R=0.92), ANFIS (R=0.95), GPR (R=0.945), and MVLR (R=0.89) to estimate the tensile strength. The average BTS measured in the laboratory and predicted by all 5 methods is 6.62 and 6.71 MPa, respectively, which shows the very high precision of the investigated methods. Analysis of model criteria using statistical analysis for developed relationships revealed that there is sufficient accuracy to use the empirical equations.