Probable chronic renal failure caused by Lonomia caterpillar envenomation

Abstract

Erucism is a skin reaction to envenomation from certain poisonous caterpillar bristles. In Brazil, most reports of erucism provoked by Lonomia caterpillars are from the southern region. Most manifestations of erucism are local and include burning pain, itching, local hyperthermia and, rarely, blisters (benign symptoms with spontaneous regression in a few hours). General symptoms such as nausea and vomiting, headache, fever, myalgia, abdominal pain and conjunctivitis may also occur. Uncommon symptoms include arthritis, coagulation disorders (manifested as bruising and bleeding), intracerebral hemorrhage and acute renal failure, which comprise serious complications. The present study reports the case of 60-year-old patient from Rio de Janeiro state, Brazil, who came into contact with a caterpillar and developed, a few days later, chronic renal disease.

Acute kidney injury due to tropical infectious diseases and animal venoms: a tale of 2 continents

“…243,244,249 Development of CKD following Lonomia venom-associated AKI was described in 5 patients. 245,250 Loxosceles. Spiders of the genus Loxosceles are distributed worldwide, including SA and LA.…”

Renal and vascular effects of kallikrein inhibition in a model of Lonomia obliqua venom-induced acute kidney injury

“…Envenomed victims display systemic hemorrhage secondary to intravascular disseminated coagulation [ for review see 1,2] . Frequently, the clinical profile evolves to acute kidney injury (AKI), which is the main cause of death following this type of envenomation [3–5] . In experimental models, L .…”

What’s Eating You? Caterpillars

“…reported case of a patient whose Lonomia caterpillar sting went unrecognized until a week after the accident ended with progression to stage V chronic renal disease. 12 Recent research has focused on the specific mechanism of injury caused by Lonomia species. A study found that the venom of L obliqua causes cytoskeleton rearrangement and migration in vascular smooth muscle cells (VSMCs) by inducing formation of reactive oxygen species through activation of nicotinamide adenine dinucleotide phosphate oxidase.…”