2008
DOI: 10.1080/00480169.2008.36815
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Probable malignant catarrhal fever presented as transient generalised crusting dermatitis in a cow

Abstract: Malignant catarrhal fever should be considered in cases of ulcerative skin disease in cattle. The disease is difficult to diagnose, and a combination of skin histology as well as PCR is required. Although probably rare, it appears complete recovery from MCF is possible when the disease is confined to the skin.

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Cited by 12 publications
(21 citation statements)
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“…2,4 Extensive skin disease can also be a feature of MCF in cattle, including a dermal infiltrate of multinucleate giant cells, in the absence of other clinical signs. 3,5,8 In the goat reported here, infection with OvHV-2 most likely resulted from exposure to sheep on the same farm. Although the OvHV-2 status of the sheep was unknown, essentially all sheep in the United Kingdom are considered to be OvHV-2 carriers.…”
Section: Discussionmentioning
confidence: 84%
“…2,4 Extensive skin disease can also be a feature of MCF in cattle, including a dermal infiltrate of multinucleate giant cells, in the absence of other clinical signs. 3,5,8 In the goat reported here, infection with OvHV-2 most likely resulted from exposure to sheep on the same farm. Although the OvHV-2 status of the sheep was unknown, essentially all sheep in the United Kingdom are considered to be OvHV-2 carriers.…”
Section: Discussionmentioning
confidence: 84%
“…On the one hand, the water buffaloes seemed to be more susceptible than cattle to infection with either virus; on the other hand, the case fatality rate among water buffaloes was lower than the perceived lethality among cattle [34] . However, recent reports from countries with a high concentration of farms, where OvHV-2 reservoir species are kept together with MCF-indicator species, suggested an increasing incidence of non-lethal outcomes of MCF, which also involved either subclinical cases among cattle, and more chronic, cutaneous forms of the disease [50] , [62] – [64] . These observations may signify that either OvHV-2 has a capacity to adapt to new hosts upon serial passaging or else that the cattle in those countries are selected to become resistant to MCF.…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, vasculitis has been reported as a consequence of systemic herpesvirus infections caused by malignant catarrhal fever (MCF) (16) and , and bovine endothelial cell cultures were found to be susceptible to BoHV-4 infection (18). Although the pathogenesis of vasculitis remains unsolved, it is usually assumed that a small fraction of infected lymphocytes induces the proliferation and deregulation of uninfected cells with a nonspecific cytotoxic effect (19).…”
mentioning
confidence: 99%