Probing Diverse Interactions of Model Amino Acids Prevalent in Aqueous Solutions of Anti-Histaminic Drug by Physicochemical Contrivance

Abstract

The diverse molecular interactions key to the system of the ternary composition of (Drug+ water + amino acids) were comprehended through the evaluation of physicochemical parameters namely density, viscosity, refractive index and conductance at four different (temperatures), and that of surface tension at (298.15K) held at atmospheric pressure. These aforementioned parameters were highly conclusive of the existence of significant molecular interactions in the experimental ternary system. This follows to establish that the extent of solutesolvent interactions is, but a function of solute concentration. An insight into such diverse interactions and gain in its understanding is the prime base for designing efficient drug deliveries and applications with similar interactions at its core.