Probiotic Bacteria in Microbiome against Allergy

Abstract

According to the World Allergy Organization (WAO), approximately 20% of the global population suffers from allergies. As per ongoing investigations, their pervasiveness is expanding comprehensively. Allergic diseases are significant because of the high prevalence and constant increase in their costs and adverse effects on human life. Probiotics are proposed as an intervention for the prevention and treatment of allergic diseases. Various mechanisms are considered for the anti-allergic effects of probiotic properties, like detecting related molecular patterns, including DNA motifs or lipopolysaccharides (LPS) of the bacteria, through interaction with host immune systems by Toll-like receptors. In this chapter, the microbiome, allergy, and the role of immunomodulatory probiotics against allergy are discussed.

Role of Nutribiotics in Skin Care

“…Moreover, other studies showed that using probiotics during gestation and early life can reduce the incidence and severity of atopic dermatitis via immune modulation and by promoting the maturation of the gut barrier's function [130,135,136]. Additionally, probiotics were investigated to treat different allergy illnesses, including atopic dermatitis, asthma, allergic rhinitis, and food allergy [137]. Despite of this, Małolepsza and Dembowski [138], after reviewing several studies, concluded that alterations in the intestinal microbiome play an important role not only in the development and aggravation of many skin diseases but also influence skin aging, although more research is necessary to evaluate the impact of probiotics.…”

Role of Nutribiotics in Skin Care

“…Orally administration of probiotics affects the intestinal microbiome and can improve skin conditions such as atopic dermatitis, acne, or rosacea [133,134], and also other studies showed that using probiotics during gestation and early life could reduce the incidence and severity of atopic dermatitis, by immune modulation and promoting the maturation of the gut barrier function [135,130,136]. Additionally, probiotics are investigated to treat different allergy illnesses, including atopic dermatitis, asthma, allergic rhinitis, and food allergy [137]. Despite of that, Małolepsza & Dembowski [138], after reviewing several studies, concluded that alterations in the intestinal microbiome play an important role not only in the development and aggravation of many skin diseases, but also influence skin aging, although it is necessary more research to evaluate the impact of probiotics.…”