Probiotic Encapsulation Technology: From Microencapsulation to Release into the Gut

Gbassi, Gildas K.; Vandamme, Thierry F.

doi:10.3390/pharmaceutics4010149

Cited by 190 publications

(170 citation statements)

References 65 publications

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“…PET, a colloidal delivery system whose concept is encapsulating a bacterium in a gel-like suspension, then packing the substance into a miniature-sized final product that has the enhanced power of functionality and the ability to control the release of the core, increasing the stability of the pharmaceuticalgrade nutrient [18,19]. It provided access to the probiotic to bypass the unsuitable environment such as the acid and bile-rich stomach.…”

Section: Encapsulation Of Probiotic Bacteriamentioning

confidence: 99%

Nanotechnology and its Partnership with Synbiotics

Caneus¹

2017

JNMR

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In the realm of nanotechnology, there are no barriers aside from a researcher's imagination that can prevent the field from being a reputable force. The emergence of nanomedicine is an actual benefit in the increased interest placed within the food sector. As the field evolves, it is in a constant state of improvement. Researchers seek for innovative ways to combine the fundamentals of Nano-measurement with the emerging importance of colon health. Nanotechnology is becoming a valuable source of supportive help to the once known golden standards of gastroenterology. The once preventative measures used for colon carcinomas, ulcerative colitis, and Celiac Disease and an option for post treatment bacterial and viral enteritis, has gotten the sense of melioration in the technology. There is an importance in understanding the microbial flora of the gut, and the efforts to maintain it and with promising results; nanotechnology is becoming increasingly important for the food sector.

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Section: Encapsulation Of Probiotic Bacteriamentioning

confidence: 99%

Nanotechnology and its Partnership with Synbiotics

Caneus¹

2017

JNMR

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“…Uygulamada atomizer içerisinde hem çekirdek ad› verilen kaplanacak materyal hem de kaplama materyali bir arada bulunmaktad›r. Bu yöntemde en büyük dezavantaj yüksek s›cakl›klara ihtiyaç duyulmas› iken son üründe istenen miktarda hücre canl›l›¤›n› koruman›n da zor oldu¤u bildirilmifltir (30). Yüksek s›cakl›klarda çal›flman›n enkapsülasyon uygulamalar›nda belli sorunlara sebep oldu¤unun rapor edilmesi üzerine (31,32), baz› araflt›rmac›lar taraf›ndan daha düflük s›cakl›klarda enkapsülasyon yöntemlerinin gelifltirilmesi üzerine çal›flmalara odaklan›lm›flt›r (33).…”

Section: Bakteri̇yofaj Enkapsülasyonu Potansi̇yel Uygulamalariunclassified

Bakteri̇yofaj Enkapsülasyonu Ve Potansi̇yel Uygulamalari

Saygılı¹,

Karagözlü²

2017

GIDA

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ÖzetEnkapsülasyon, aktif olan maddenin çevresinde uygun kaplama materyali ile koruyucu bir zar oluflturulmas› temeline dayanmaktad›r. G›da endüstrisinde mikroenkapsülasyon istenen bileflenin d›fl etkenlere karfl› korunmas›, baz› özelliklerinin sürdürülebilmesi, kolay tafl›nmas›, tat ve koku maskeleme, oluflabilecek reaksiyonlar›n önüne geçme gibi amaçlarla kullan›lmas›na ra¤men koruyucu ve tedavi amaçl› fajlar›n enkapsülasyonunun da oldukça etkili bir yöntem olarak uygulanabildi¤i bilinmektedir. Bakteriyofajlar 20. yüzy›l›n bafllar›ndan beri bakteriyel enfeksiyonlara karfl› koruma ve tedavi amac›yla kullan›lm›fl ancak artan antibiyotik tüketimi, fajlar›n tedavi amaçl› kullan›m›n›n önüne geçmifltir. En önemli özelli¤i yüksek spesifitesi olan bakteriyofajlar, çiftlik hayvanlar›nda patojen kolonizasyonunun azalt›lmas› (faj tedavisi), çi¤ süt, et ve taze g›dalarda dekontaminasyon (biyokontrol), ekipman yüzeylerinde sanitasyon (biyosanitasyon), haz›r g›dalarda raf ömrü uzatmak (biyoprezervasyon) amac›yla uygulanabilen etkin bir yöntem olarak karfl›m›za ç›kmaktad›r. Bakteriyofaj enkapsülasyon uygulamalar›nda, fonksiyonel kaplama uygulamalar›ndaki geliflmelere paralel olarak daha uygun maliyetli ve daha uzun süre muhafaza edilebilen mikrokapsül teknolojilerinin gelifltirilmesine ihtiyaç duyulmaktad›r.Anahtar kelimeler: Enkapsülasyon, bakteriyofaj, faj tedavi, biyokontrol, biyosanitasyon, biyoprezervasyon BACTERIOPHAGE ENCAPSULATION AND POTENTIAL APPLICATIONS AbstractEncapsulation is based on forming a protective membrane around the active substance with a suitable coating material. Although microencapsulation is applied for purposes including protection of some components against external factors, preservation of some features, easy handling, flavor and odor masking, prevention of some reactions, it is known that the phage encapsulation can be highly effective for protection and treatment purposes. Since the early 20th century, bacteriophages are used for the prevention and treatment of bacterial infections, however the increase in the consumption of antibiotics has prevented the use of phages for treatment. One of the most important properties of bacteriophages is the high specificity. They are effectively used for the reduction of pathogen colonization in farm animals (phage therapy), decontamination of raw milk, meat and fresh food (biocontrol), sanitation of equipment surfaces (biosanitation), extending the shelf life of prepared foods (biopreservation). There is a need for the development of microcapsule technology which is relatively cost effective and allows longer storage periods in parallel with the developments in functional coating applications.

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“…The relevant literature proposes the use of encapsulation techniques to stabilize bacteria, thereby enhancing their viability during production, storage, and handling [24]. This can be performed using different strategies like emulsion, extrusion and recently spray-drying techniques [25][26][27].…”

Section: Editorialmentioning

confidence: 99%