PROBIÓTICOS NA RAÇÃO PARA O CONTROLE DE Salmonella Minnesota EM FRANGOS DE CORTE

Muñíz, Eduardo; Pickler, Larissa; Lourenço, Miguel L.; Westphal, Patrick; Kuritza, Leandro Nagae; Santín, Elizabeth

doi:10.5380/avs.v18i3.29831

Cited by 3 publications

(4 citation statements)

References 8 publications

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“…In this study, histology observations in ileum seemed atypical as reported in other Salmonella trials ( 37 , 38 ) suggesting a considerable variation on ileal morphology when Salmonella is present. This variation in ileum histology could be associated with the fact that Salmonella has the cecum as target tissue.…”

Section: Discussionsupporting

confidence: 44%

“…Furthermore, mucins may exert prebiotic-type effects as carbohydrate content can account for 90% of their weight ( 44 ). Muniz et al ( 37 ) observed similar effects when four different probiotics increased the proliferation of goblet cells in ileum. The association of probiotics with epithelial cells might be sufficient to trigger signaling cascades at epithelium level and activate underlying immune cells in lamina propria ( 45 ).…”

Section: Discussionmentioning

confidence: 79%

“…According to Van Immerseel et al ( 36 ), the encounter between specialized epithelial cells and microorganisms quickly stimulates the release of proinflammatory chemokines that attract innate immune cells (i.e., granulocytes and macrophages), which are able to trigger a wide range of new immune responses such as the emergence of T helper lymphocytes (CD4+ cells). An early increase in CD4+ and CD8+ cells has been reported in chickens fed probiotics ( 37 – 39 ). In some cases, Salmonella cells invade and multiply within the macrophages ( 40 – 42 ) and widely distribute themselves in the lymphoid and nonlymphoid tissues, facilitating their spreading to various organs of the host.…”

Section: Discussionmentioning

confidence: 87%

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Effect of Feeding Bacillus subtilis Spores to Broilers Challenged with Salmonella enterica serovar Heidelberg Brazilian Strain UFPR1 on Performance, Immune Response, and Gut Health

et al. 2018

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Salmonellosis is a poultry industry and public health concern worldwide. Recently, Salmonella enterica serovar Heidelberg (SH) has been reported in broilers in Brazil. The effect of feeding a blend of three strains of Bacillus subtilis (PRO) was studied in broilers orally challenged (107 CFU/chick) or not with a SH isolated in south of Brazil (UFPR1 strain). Twelve male Cobb 500 broilers per pen were randomly assigned to six treatments in a 3 × 2 factorial experiment where PRO was added at 0, 250, or 500 g/ton of broiler feed and fed to either SH-challenged (SH Control, SH + PRO 250, and SH + PRO 500) or non-challenged birds (Control, PRO 250, and PRO 500). Broiler performance, histologic alterations in intestinal morphology, Salmonella quantification and immune cells counts in liver (macrophages, T CD4+ and T CD8+) were analyzed. Changes in the intestinal microbiota of broilers were also studied by metagenomics for Control, SH Control, SH + PRO 250, and SH + PRO 500 only. Feeding PRO at 250 or 500 g/ton reduced SH counts and incidence in liver and cecum at 21 days of age. It was observed that PRO groups increased the macrophage mobilization to the liver in SH-challenged birds (P < 0.05) but reduced these cells in the liver of non-challenged birds, showing an interesting immune cell dynamics effect. PRO at 250 g/ton did not affect gut histology, but improved animal performance (P < 0.05) while PRO at 500/ton did not affect animal performance but increased histologic alteration related to activation of the defense response in the ileum in SH challenged birds compared to control birds (P < 0.05). SH + PRO 500 group presented a more diverse cecal microbiota (Shannon–Wiener index; P < 0.05) compared to Control and SH Control groups; while SH + PRO 250 had greater ileal richness (JackkNife index) compared to Control (P < 0.05). PRO was effective in reducing Salmonella colonization in liver and cecum when fed at 250 or 500 g/ton to broilers inoculated with SH strain UFPR1. PRO promotes positive alterations in performance (at 250 g/ton), immune modulatory effect in the gastrointestinal tract, SH reduction, and intestinal microbiota modulation.

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Section: Discussionsupporting

confidence: 44%

Section: Discussionmentioning

confidence: 79%

Section: Discussionmentioning

confidence: 87%

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Effect of Feeding Bacillus subtilis Spores to Broilers Challenged with Salmonella enterica serovar Heidelberg Brazilian Strain UFPR1 on Performance, Immune Response, and Gut Health

et al. 2018

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“…Twenty fields per treatment were scanned under a light microscope at 40x magnification. For the analysis of CD4+ and CD8+ lymphocytes and macrophages by immunohistochemistry, samples were processed according to Muniz et al, (2013) and 20 fields were scanned per experimental group, using a light microscope at 100x magnification (Olympus BX41 Olympus USA).…”

Section: Influence Of Covering Reused Broiler Litter With Plastic Canmentioning

confidence: 99%

Influence of Covering Reused Broiler Litter with Plastic Canvas on Litter Characteristics and Bacteriology and the Subsequent Immunity and Microbiology of Broilers

Mesa

Lourenço

Souza

et al. 2016

Rev. Bras. Cienc. Avic.

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In broiler production, the litter is reused for consecutives flocks, and it is treated during down time between flocks to reduce its microbial load. Although covering the litter with a plastic canvas is a common litter treatment in the field, there is little scientific information available on its efficacy. The aim of this study was to evaluate the effects of covering broiler litter with a plastic canvas for eight days on litter microbiological, physical, and chemical parameters, and on the intestinal microbiota and immunity of broilers. In the first trial, reused litter from a previous flock was distributed into three treatments, with six replicates each: L1 (negative control, litter free from Salmonella Enteritidis (SE) and Eimeria maxima (EM) and not covered), L2 (positive control, litter with SE and EM, and not covered), and L3 (litter with SE and EM, and covered with plastic canvas for eight days). Litter total bacteria, Enterobacteria, Lactobacillus, SE, and EM counts, and litter pH, temperature, moisture, and ammonia emission were determined on days 1 and 8. In the second trial, broilers were housed on those litters according to the treatments described above, and their intestinal microbiota, gut CD4+ and CD8+ lymphocytes and macrophages, and liver and intestinal proinflammatory interleukin (IFN-γ, IL-1β e IL-18) levels were evaluated on days 14 and 28. A significant reduction of litter bacterial populations was observed in the litter covered with plastic canvas. A significantly higher mRNA IFN-γ gene expression (12.5-fold) was observed in the jejunum and liver of broilers reared on the litter with Enterobacteria counts. No EM reduction was observed in the covered litter. Covering reused broiler litter with plastic canvas reduces initial litter bacterial load as a result of the interaction between physical and chemical parameters.

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The use of probiotics in animal feeding for safe production and as potential alternatives to antibiotics

et al. 2021

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Although the production of safe food for human consumption is the primary purpose for animal rearing, the environment and well-being of the animals must also be taken into consideration. Based on microbiological point of view, the production of healthy food from animals involves considering foodborne pathogens, on the one hand and on the other hand, the methods used to fight against germs during breeding. The conventional method to control or prevent bacterial infections in farming is the use antibiotics. However, the banning of these compounds as growth promoters caused many changes in animal breeding and their use has since been limited to the treatment and prevention of bacterial infections. In this function, their importance no longer needs to be demonstrated, but unfortunately, their excessive and abusive use have led to a double problem which can have harmful consequences on consumer health: Resistance to antibiotics and the presence of antibiotic residues in food. The use of probiotics appears to be a suitable alternative to overcome these problems because of their ability to modulate the immune system and intestinal microflora, and further considering their antagonistic role against certain pathogenic bacteria and their ability to play the role of growth factor (sometimes associated with prebiotics) when used as feed additives. This review aims to highlight some of the negative effects of the use of antibiotics in animal rearing as well as emphasize the current knowledge on the use of probiotics as a feed additive, their influence on animal production and their potential utility as an alternative to conventional antibiotics, particularly in poultry, pig, and fish farming.

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PROBIÓTICOS NA RAÇÃO PARA O CONTROLE DE Salmonella Minnesota EM FRANGOS DE CORTE

Cited by 3 publications

References 8 publications

Effect of Feeding Bacillus subtilis Spores to Broilers Challenged with Salmonella enterica serovar Heidelberg Brazilian Strain UFPR1 on Performance, Immune Response, and Gut Health

Effect of Feeding Bacillus subtilis Spores to Broilers Challenged with Salmonella enterica serovar Heidelberg Brazilian Strain UFPR1 on Performance, Immune Response, and Gut Health

Influence of Covering Reused Broiler Litter with Plastic Canvas on Litter Characteristics and Bacteriology and the Subsequent Immunity and Microbiology of Broilers

The use of probiotics in animal feeding for safe production and as potential alternatives to antibiotics

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