Probiotics and oral health: A systematic review

Seminario-Amez, María; López‐López, José; Estrugo‐Devesa, Albert; Ayuso‐Montero, Raúl; Jané‐Salas, Enric

doi:10.4317/medoral.21494

Cited by 113 publications

(99 citation statements)

References 39 publications

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“…So, despite an incomplete understanding of the healthy gut microbiome and the pathogenesis of ulcerative colitis, microbiome studies have enabled researchers to formulate and test hypotheses that have produced promising interventions. The same approach has been tested to a limited extent for its potential to influence oral health and reduce counts of Streptococcus mutans (Seminario‐Amez, Lopez‐Lopez, Estrugo‐Devesa, Ayuso‐Montero, & Jane‐Salas, ) and Candida (Keller & Kragelund, ) with variable results.…”

Section: Discussionmentioning

confidence: 99%

World Workshop on Oral Medicine VII: Targeting the oral microbiome Part 2: Current knowledge on malignant and potentially malignant oral disorders

et al. 2019

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Objective The World Workshop on Oral Medicine VII chose the oral microbiome as a focus area. Part 1 presents the methodological state of the science for oral microbiome studies. Part 2 was guided by the question: What is currently known about the microbiome associated with oral squamous cell carcinoma and potentially malignant disorders of the oral mucosa? Materials and Methods A scoping review methodology was followed to identify and analyse relevant studies on the composition and potential functions of the oral microbiota using high‐throughput sequencing techniques. The authors performed searches in PubMed and EMBASE. After removal of duplicates, a total of 239 potentially studies were identified. Results Twenty‐three studies on oral squamous cell carcinoma, two on oral leukoplakia and four on oral lichen planus were included with substantial differences in diagnostic criteria, sample type, region sequenced and sequencing method utilised. The majority of studies focused on bacterial identification and recorded statistically significant differences in the oral microbiota associated with health and disease. However, even when comparing studies of similar methodology, the microbial differences between health and disease varied considerably. No consensus on the composition of the microbiomes associated with these conditions on genus and species level could be obtained. Six studies on oral squamous cell carcinoma had included in silico predicted microbial functions (genes and/or pathways) and found some similarities between the studies. Conclusions Attempts to reveal the microbiome associated with oral mucosal diseases are still in its infancy, and the studies demonstrate significant clinical and methodological heterogeneity across disease categories. The immense richness and diversity of the microbiota clearly illustrate that there is a need for additional methodologically comparable studies utilising deep sequencing approaches in significant cohorts of subjects together with functional analyses. Our hope is that following the recipe as outlined in our preceding companion paper, that is Part 1, will enhance achieving this in the future and elucidate the role of the oral microbiome in oral squamous cell carcinoma and potentially malignant disorders of the oral mucosa.

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Section: Discussionmentioning

confidence: 99%

World Workshop on Oral Medicine VII: Targeting the oral microbiome Part 2: Current knowledge on malignant and potentially malignant oral disorders

et al. 2019

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“…The Jadad scale ranges from 0–5. If the Jadad score was ≥3 points, the trial was considered high‐quality research, whereas if the Jadad score was ≤2 points, the study was considered a low‐quality trial (Espí‐López, Arnal‐Gómez, Balasch‐Bernat, & Inglés, ; Jadad et al, ; Seminario‐Amez, López‐López, Estrugo‐Devesa, Ayuso‐Montero, & Jané‐Salas, ; Zhang, Lan, Pen, & Li, ).…”

Section: The Reviewmentioning

confidence: 99%

Effectiveness of a psychoeducational intervention for caregivers of People With Dementia with regard to burden, anxiety and depression: A systematic review

Frías

Garcia‐Pascual

Montoro

et al. 2020

Journal of Advanced Nursing

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Aim To assess the effectiveness of psychoeducational interventions with respect to burden, anxiety and depression in family caregivers of People With Dementia living at home. Background In dementia, the family assumes the role of main caregiver, maintaining the patient in a good state of health. Nevertheless, burden, anxiety and depression may have negative repercussions in caregivers. Therefore, professional supports through psychoeducational programmes are recommended as interventions for improving caregivers' health. Design A quantitative systematic review. Data Sources Electronic searches were performed in CINAHL/AMED/CENTRAL/Web of Science/LILACS/PUBMED from January 2005–August 2018. Review Methods The review was conducted using the JADAD scale to assess bias risk and the quality of the randomized controlled trials (RCTs) and the CONSORT instrument to assess study quality report. The extracted data were reviewed by independent reviewer pairs. The review was reported using PRISMA. Results A total of 18 RCTs met inclusion criteria. Seven were classified as Technology‐based Interventions and 11 as Group‐based Interventions. Conclusion Psychoeducational interventions for caregivers allow them to increase their knowledge of the illness, develop problem‐solving skills and facilitate social support. Technology‐based Interventions significantly affect burden while Group‐based Interventions affect anxiety, depression, insomnia and burden and quality of life and self‐efficacy. Impact Research findings can be used to classify caregivers in future interventions according to illness stage to obtain more precise results.

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“…Utilizing probiotics as a supplement in foods that are potentially cariogenic is an interesting approach for improving oral health, as seen in a number of recent studies aimed at controlling caries, periodontal disease and oral candidiasis. 20 In this study, we chose cake as a carrier of B. coagulans to reduce the S. mutans count. This choice is consistent with the prevalent consumption of sucrosecontaining snacks in modern societies, especially among children.…”

Section: Discussionmentioning

confidence: 99%

Comparison of the effect of regular and probiotic cake (Bacillus coagulans) on salivary pH and Streptococcus mutans count

et al. 2019

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Background. Dental caries is considered the most common infectious disease in humans worldwide. Cariogenesis is the outcome of a complex interaction between the host's oral flora and diet. The consumption of snacks such as cake, which have the potential to promote dental caries, has increased.Objectives. The aim of this study was to investigate the effect of including probiotic bacteria (Bacillus coagulans -B. coagulans) in consumed snack cake on the Streptococcus mutans (S. mutans) count and salivary pH.Material and methods. We conducted a randomized, double-blind, cross-sectional cohort study on 40 healthy volunteers. The subjects were divided into 2 groups. In the 1 st group, the subjects consumed probiotic cake as breakfast for 1 week and then, following a 4-week wash-out period, consumed regular cake as breakfast for 1 week. In the other group, the administration of probiotic and regular cake was reversed. For both groups, samples of at least 5 mL of non-stimulated saliva were collected using the spitting technique before and after the 1 st and the 6 th week. A colony counter was used to determine the number of S. mutans colonies. Salivary pH was measured before eating (8-9 a.m.). Results.We detected no statistically significant difference in the S. mutans count before and after the consumption of probiotic cake, but noted a statistically significant difference in the count before and after the consumption of regular cake. We did not detect a significant difference in salivary pH with respect to the consumption of probiotic and regular cake, although the consumption of both foods caused a drop in salivary pH.Conclusions. The addition of probiotic bacteria to sweet snack cake caused a minimal increase in the salivary count of S. mutans, a bacterial species with a definite role in cariogenesis, but did not impact salivary pH. Since probiotic cake has a slight impact on the S. mutans count, it is preferred over regular cake as a snack food. Cite asKoopaie M, Fatahzadeh M, Jahangir S, Bakhtiari R. Comparison of the effect of regular and probiotic cake (Bacillus coagulans) on salivary pH and Streptococcus mutans count.

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Probiotics and oral health: A systematic review

Cited by 113 publications

References 39 publications

World Workshop on Oral Medicine VII: Targeting the oral microbiome Part 2: Current knowledge on malignant and potentially malignant oral disorders

World Workshop on Oral Medicine VII: Targeting the oral microbiome Part 2: Current knowledge on malignant and potentially malignant oral disorders

Effectiveness of a psychoeducational intervention for caregivers of People With Dementia with regard to burden, anxiety and depression: A systematic review

Comparison of the effect of regular and probiotic cake (Bacillus coagulans) on salivary pH and Streptococcus mutans count

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