Probiotics and prebiotics in the prevention and management of human cancers (colon cancer, stomach cancer, breast cancer, and cervix cancer )

Jampílek, Josef; Kráľová, Katarína; Bella, Vladimír

doi:10.1016/b978-0-12-823733-5.00009-x

Cited by 5 publications

(2 citation statements)

References 183 publications

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“…This research also identified a positive, albeit nonsignificant, relationship between SC cases and probiotic usage. Probiotics are widely used as dietary supplements in the general population, and their application to alleviate the adverse effects of treatment in cancer patients is progressively increasing (35). Surgical intervention remains the primary treatment for SC, with diarrhea being a prevalent complication Mod Care J.…”

Section: Discussionmentioning

confidence: 99%

Tendency to Consume Probiotics in the General Population: An Ecological Study

Rabiee,

Mousavi

2024

Mod Care J

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Background: Reports indicate that probiotics have beneficial effects on both the prevention and treatment of numerous diseases. Objectives: This study aims to explore the overall inclination toward probiotic consumption, its trends, and its association with common gastrointestinal diseases. Methods: We conducted an ecological study utilizing Google Trends (GTs) and Global Concern data. We analyzed search terms related to "probiotic," "Irritable Bowel Syndrome (IBS)," "Peptic," "Constipation," "Diarrhea," and "Stomach Cancer (SC)" across all searches performed on GTs from January 2014 to July 2023. Results: Globally and in Iran, there has been an increasing interest in consuming probiotics over time. This increase is linked to a rise in cases of stomach cancer and irritable bowel syndrome, which, in turn, boosts the propensity to utilize probiotics. Globally, there is a direct correlation between probiotic consumption and IBS (R = +0.69, P = 0.0001), peptic disorders (R = +0.71, P = 0.001), Constipation (R = +0.93, P = 0.001), and diarrhea (R = +0.89, P = 0.001). In Iran, significant direct correlations were found between probiotic consumption and both constipation (R = +0.36, P = 0.001) and diarrhea (R = +0.40, P = 0.001). Among probiotic-containing products, yogurt was preferred over others worldwide and in Iran. Conclusions: The interest in probiotic use is high globally and in Iran. Consequently, there is a need for strategies to educate the public about the areas where the benefits of probiotics are well-supported by evidence and where information is either weak or lacking.

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Section: Discussionmentioning

confidence: 99%

Tendency to Consume Probiotics in the General Population: An Ecological Study

Rabiee,

Mousavi

2024

Mod Care J

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“…Probiotic bacteria exhibit anticancer effects through a specific group of microbes, including Bifidobacterium and Lactobacillus species. They reduce the carcinogenic enzyme levels of the colonic through various defensive mechanisms, including antimutagenic organic acids production, improving the host immune system, intestinal permeability regulation, and microflora balance [ 59 , 60 , 61 ]. Moreover, evidence recommends that foodstuffs containing probiotic bacteria possibly contribute to cardiac disorder by reducing serum cholesterol levels and controlling blood pressure.…”

Section: Probiotic Isolates and Their Health Advantagesmentioning

confidence: 99%

Pharmacological Efficacy of Probiotics in Respiratory Viral Infections: A Comprehensive Review

Wahab

Almaghaslah

Mahmood

et al. 2022

JPM

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Mortality and morbidity from influenza and other respiratory viruses are significant causes of concern worldwide. Infections in the respiratory tract are often underappreciated because they tend to be mild and incapacitated. On the other hand, these infections are regarded as a common concern in clinical practice. Antibiotics are used to treat bacterial infections, albeit this is becoming more challenging since many of the more prevalent infection causes have acquired a wide range of antimicrobial resistance. Resistance to frontline treatment medications is constantly rising, necessitating the development of new antiviral agents. Probiotics are one of several medications explored to treat respiratory viral infection (RVI). As a result, certain probiotics effectively prevent gastrointestinal dysbiosis and decrease the likelihood of secondary infections. Various probiotic bacterias and their metabolites have shown immunomodulating and antiviral properties. Unfortunately, the mechanisms by which probiotics are effective in the fight against viral infections are sometimes unclear. This comprehensive review has addressed probiotic strains, dosage regimens, production procedures, delivery systems, and pre-clinical and clinical research. In particular, novel probiotics’ fight against RVIs is the impetus for this study. Finally, this review may explore the potential of probiotic bacterias and their metabolites to treat RVIs. It is expected that probiotic-based antiviral research would be benefitted from this review’s findings.

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