Probiotics for the treatment of bacterial vaginosis

Senok, Abiola; Verstraelen, Hans; Temmerman, Marleen; Botta, Giuseppe

doi:10.1002/14651858.cd006289

Cited by 43 publications

(58 citation statements)

References 29 publications

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“…A Cochrane review of 2009 did not find probiotics useful in the treatment of BV [13] while another concluded they were effective when combined with antibiotics [14]. Also, supplements of the probiotic lactobacillus, alongside the antibiotic metronidazole, appeared to increase metronidazole's effectiveness [10].…”

Section: Introductionmentioning

confidence: 99%

Nugent Scores of Pregnant Women in a Tertiary Institution in Nigeria

Ajani¹,

Oduyebo²,

Haruna³

et al. 2012

AiM

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Background: Bacterial Vaginosis (BV) is an imbalance of the vaginal normal flora, and it is asymptomatic in most women. Therefore, one of the major ways of diagnosing BV is demonstration of an abnormal flora in the vagina. This can be achieved through various methods including Nugent score. In view of the association of BV with obstetric/gynaecological complications and high rate of HIV transmission, it is desirable to know the prevalence of BV in pregnant women. Knowledge of risk factors will also help to design preventive measures. Methodology: A prospective study was performed to determine the prevalence of BV among pregnant women. High vaginal swabs (HVS) were collected and smears made were Gram stained and scored by the Nugent method. A predesigned questionnaire was also used to obtain information on possible risk factors. Associations between categorical variables were assessed using chi square test and fisher's exact test as appropriate. Result: Three hundred married women aged between 18 and 45 years were studied. The prevalence of BV was 64.3%, 25% had intermediate and 10.7% had negative Nugent scores. BV rates were high across all age groups, educational background, ethnicity, parity, HIV status, and occupation. The occurrence of BV was higher (75.5%) among gestational age group ≤ 30 weeks (p < 0.05), in women who had sex more than twice within a week (p < 0.05) and in women who engaged in unskilled labour (p < 0.05). Conclusion: Bacterial vaginosis is a very common condition among the studied population. This high prevalence may necessitate routine screening and treatment during antenatal care in preventing the associated adverse effects of BV during pregnancy and childbirth.

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Section: Introductionmentioning

confidence: 99%

Nugent Scores of Pregnant Women in a Tertiary Institution in Nigeria

Ajani¹,

Oduyebo²,

Haruna³

et al. 2012

AiM

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“…Effectiveness of chlamydia screening in clinical trials 307 The rationale for chlamydia screening is that testing should detect asymptomatic infections in 308 women before they cause PID or other reproductive complications; if a large enough 309 proportion of the population can be screened, reduced incidence and prevalence of infection 310 ought to further prevent reproductive complications indirectly by reducing exposure to 311 infection. 91 …”

mentioning

confidence: 99%

Sexually transmitted infections: challenges ahead

Unemo

Bradshaw

Hocking

et al. 2017

The Lancet Infectious Diseases

588

469

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“…Non-antibiotic based treatment with probiotic lactobacilli or lactic acid preparations have not yielded consistently reproducible evidence of efficacy as treatments for BV and no recommendation on their use can be made at present (29).…”

Section: Diagnosismentioning

confidence: 99%

Genital discharge and genital ulceration

William¹

2014

Acute Medicine

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Probiotics for the treatment of bacterial vaginosis

Cited by 43 publications

References 29 publications

Nugent Scores of Pregnant Women in a Tertiary Institution in Nigeria

Nugent Scores of Pregnant Women in a Tertiary Institution in Nigeria

Sexually transmitted infections: challenges ahead

Genital discharge and genital ulceration

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