Probiotics are Nonpathogenic microorganisms that are beneficial to one's nutritional health and are usually found in certain foods or supplements. They are typically bacteria, such as Lactobacillus, Bifidobacterium, Streptococcus, Leuconostocmesenteroides, Pediococcus, Propionibacterium, Bacillus, and Enterococcus faecium but can also be Yeast and molds. Probiotics help to maintain a healthy balance of gut microflora, which is important for digestion and overall health. They can also help with conditions such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), allergies, ulcerative colitis, Crohn's disease, and even mental health issues. Probiotics may also play a role in preventing and treating other conditions such as urinary tract infections (UTIs), vaginal yeast infections, skin conditions like eczema, and even the common cold. Probiotics are involved in things like food digestion, the production of beneficial substances to eliminate harmful microbes, completing the roles of the digestive enzymes that were either not produced or had defects in their genes, maintaining the pH of the digestive system, and other things. Probiotics will improve the performance of our digestive system's biological fermenters (Ghoshal et al. 2022;Song et al 2023;Su et al. 2022). Prebiotics like FOS, GOS, XOS, inulin, and fructans are the most popular fibers that, when combined with probiotics, are known as synbiotics and can increase the viability of the probiotics. Numerous authors have discussed the development of probiotics, their history, and their various uses for them. In this review, we will primarily concentrate on three issues: health improvement, infection prevention, and disease management, all of which can be prevented by using various probiotics either directly or in foods.