Recently, adaptive interventions have emerged as a new perspective on prevention and treatment.Adaptive interventions resemble clinical practice in that different dosages of certain prevention or treatment components are assigned to different individuals, and/or within individuals across time, with dosage varying in response to the intervention needs of individuals. To determine intervention need and thus assign dosage, adaptive interventions use prespecified decision rules based on each participant's values on key characteristics, called tailoring variables. In this paper, we offer a conceptual framework for adaptive interventions, discuss principles underlying the design and evaluation of such interventions, and review some areas where additional research is needed.
Keywords adaptive interventions; prevention; research designFor most of the history of research-based interventions aimed at prevention and treatment, the composition and dosage of these interventions have been fixed, in other words, a single composition and dosage has been offered to all program participants. For example, a schoolbased drug abuse prevention curriculum might be delivered to all sixth graders. Every component of the intervention that may be necessary for any particular participant is included in the curriculum, and each child is given the same intervention. Although it is recognized that individuals may have different intervention needs, it is expected that the intervention is in no way diluted or made counterproductive if components that are particularly relevant for an individual are combined with components that may have less, or even no, relevance for that individual.Recently, adaptive interventions have emerged as a new perspective on research-based prevention and treatment. According to this perspective, the varying intervention needs of individuals may not be met optimally by using a single uniform composition and dosage. For this reason, an adaptive intervention assigns different dosages of certain program components across individuals, and/or within individuals across time. Dosage varies in response to the intervention needs of individuals, and dosages are assigned based on decision rules linking characteristics of the individual with specific levels and types of