“…Despite disagreements about TGMVs and appropriate risk management in TBAS, both proponents and opponents generally recognize the: (a) dramatic spread of TGMVs globally, from 1.7 to 81.0 million hectares between 1996 and 2004, being 5% of the total crop area (James, 2004), including in the Third World, where over 27.6 million hectares in 11 countries were sown to TGMVs in 2004, 34% of the global area in TGMVs; (b) importation into TBAS countries of large amounts of grain containing TGMV seed (especially from the US) (USDA FAS, 2005), (c) high probability of unintentional transgene flow, including into centers of diversity, e.g., maize transgenes documented in Mexican FVs by some studies (Alvarez-Buylla, 2003;AlvarezMorales, 2002;Quist and Chapela, 2001), the effects of which may often be irreversible (Ellstrand, 2003a), though their presence or persistence is disputed by one study (Ortiz-García et al, 2005); (d) rapid development of thirdgeneration TGMVs, including maize, that produce pharmaceutical and industrial chemicals (Andow et al, 2004;Ellstrand, 2003b); and (e) need for participation of those potentially affected is essential, not only in evaluating risks, but in all four steps in the RMP (Frewer, 2003;NRC, 2002), as well as in broader benefit-cost analysis (Nelson et al, 2004).…”