Problems of establishing the prescription of death

Indiaminov, S. I.; Zhumanov, Z.E.; Blinova, S. A

doi:10.17116/sudmed20206306145

Cited by 4 publications

(1 citation statement)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Оценка давности наступления смерти (ДНС) является одним из основных вопросов теории и практики судебномедицинского эксперта. На сегодняшний день используют огромное количество методов оценки ДНС как в раннем [1,2], так и позднем посмертном периоде [3]. Каждый из предложенных методов имеет свои неоспоримые преимущества, тем не менее остаётся множество пробелов, связанных чаще с факторами эндогенного и экзогенного характера, что делает необходимым постоянное усовершенствование знаний по данной тематике с целью достижения максимальной точности в оценке ДНС при различных условиях внешней и внутренней среды.…”

Section: Introductionunclassified

Use of microRNA to estimate time science death: review

Halikov

Анварович²,

Михайлович

et al. 2021

Russian Journal of Forensic Medicine

View full text Add to dashboard Cite

Evaluation of the prescription of death is still one of the most difficult issues in forensic medical practice. The purpose of the review was to assess the potential of using miRNAs in diagnosing the prescription of death. MicroRNAs are small non-coding RNAs that are 18 to 24 nucleotides long and are well preserved in eukaryotic cells. Their role is to regulate gene expression in biological processes during the post-transcriptional phase. MicroRNA has already proven its effectiveness in clinical medicine for the diagnosis of various diseases, and the possibility of its use in forensic medicine as a marker for assessing the prescription of death has opened up, due to its low molecular weight, tissue-specific expression and high resistance to factors of the external and internal environment. As a result of the analysis of scientific literatures, it was revealed that the internal characteristics of microRNA molecules and their high resistance to degradation make them suitable as biomarkers for assessing the duration of death, especially in the late postmortem period, however, further large-scale studies on cadaveric material are needed.

show abstract

Section: Introductionunclassified