SummaryRandom Matrix Theory has been a unifying approach in physics and mathematics. In these lectures we discuss applications of Random Matrix Theory to QCD and emphasize underlying integrable structures. In the first lecture we give an overview of QCD, its low-energy limit and the microscopic limit of the Dirac spectrum which, as we will see in the second lecture, can be described by chiral Random Matrix Theory. The main topic of the third lecture is the recent developments on the relation between the QCD partition function and integrable hierarchies (in our case the Toda lattice hierarchy). This is an efficient way to obtain the QCD Dirac spectrum from the low energy limit of the QCD partition function. Finally, we will discuss the QCD Dirac spectrum at nonzero chemical potential. We will show that the microscopic spectral density is given by the replica limit of the Toda lattice equation. Recent results by Osborn on the Dirac spectrum of full QCD will be discussed.