Procalcitonin in the Emergency Department: A potential expensive over-request that can be modulated through institutional protocols

Salinas, María; López-Garrigós, Maite; Flores, Emilio; Uris, Joaquín; Leiva‐Salinas, Carlos

doi:10.1016/j.ajem.2017.07.033

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Cited by 10 publications

(2 citation statements)

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“…Beyond the impact that the inappropriate order of a biomarker could have on patient management, the economic aspect must also be considered. Indeed, PCT is an expensive test [ 20 ]. Thus, the appropriate use of PCT is strongly sought-after.…”

Section: Discussionmentioning

confidence: 99%

A machine learning strategy to mitigate the inappropriateness of procalcitonin request in clinical practice

Agnello,

Vidali,

Ciaccio

et al. 2024

Heliyon

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Section: Discussionmentioning

confidence: 99%

A machine learning strategy to mitigate the inappropriateness of procalcitonin request in clinical practice

Agnello,

Vidali,

Ciaccio

et al. 2024

Heliyon

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“…positive blood cultures). It was also shown that these levels do not increase with viral infection, but decrease with antibiotic administration [5,6]. Under normal conditions of homeostasis, preprocalcitonin undergoes initial synthesis by thyroid C cells.…”

Section: Introductionmentioning

confidence: 99%

"Usefulness of Procalcitonin in the Suspension of Antibiotics"

Rincones

2024

BJSTR

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Background: Procalcitonin is a promising biomarker for the early detection of systemic bacterial infections; its use as a predictor for antibiotic suspension has been studied and has become relevant.Methodology: A systematic review was carried out through various databases from January 2011 to February 2022; The search and selection of articles was carried out in indexed journals in English. The following keywords were used: Procalcitonin; infections; Sepsis; Bacteria; Virus.Results: Currently there are different types of inflammatory markers, among which we can highlight procalcitonin, which has become a new biomarker for the early detection of bacterial infections, especially systemic infections. Procalcitonin levels have been shown to increase over 6 to 12 hours, and these values continue to steadily increase 2 to 4 hours after the onset of sepsis. After identifying the condition, it is advisable to measure procalcitonin every 6 to 24 hours, in order to identify the need to change the antibiotic. Conclusions:The present review offers updated and detailed information on the importance of procalcitonin as a discriminating agent for viral diseases of bacteria and thus whether or not to suspend the antibiotic.

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European society of clinical microbiology and infectious diseases guidelines for antimicrobial stewardship in emergency departments (endorsed by European association of hospital pharmacists)

Schoffelen,

Papan,

Carrara

et al. 2024

Clinical Microbiology and Infection

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Procalcitonin in the Emergency Department: A potential expensive over-request that can be modulated through institutional protocols

Cited by 10 publications

References 6 publications

A machine learning strategy to mitigate the inappropriateness of procalcitonin request in clinical practice

A machine learning strategy to mitigate the inappropriateness of procalcitonin request in clinical practice

"Usefulness of Procalcitonin in the Suspension of Antibiotics"

European society of clinical microbiology and infectious diseases guidelines for antimicrobial stewardship in emergency departments (endorsed by European association of hospital pharmacists)

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