University and college laboratories are important places to train professional and technical personnel. Various regulatory departments in colleges and universities still rely on traditional laboratory management in research projects, which are prone to problems such as untimely information and data transmission. The present study aimed to propose a new method to solve the problem of data islands, explicit ownership, conditional sharing, data safety, and efficiency during laboratory data management. Hence, this study aimed to develop a data-centered lab management system that enhances the safety of lab data management and allows the data owners of the labs to control data sharing with other users. The architecture ensures data privacy by binding data ownership with a person using a key management method. To achieve data flow safely, data ownership conversion through the process of authorization and confirmation was introduced. The designed lab management system enables laboratory regulatory departments to receive data in a secure form by using this platform, which could solve data sharing barriers. Finally, the proposed system was applied and run in different server environments by implementing data security registration, authorization, confirmation, and conditional sharing using SM2, SM4, RSA, and AES algorithms. The system was evaluated in terms of the execution time for several lab data with different sizes. The findings of this study indicate that the proposed strategy is safe and efficient for lab data sharing across domains.