“…Next to the production of chlorine, publications cover the production of hydrogen, ammonia, methane, methanol, synthetic natural gas, ethylene oxide and formic acid. The studies considered either the process designed as implemented in the industry today (Gruber 2017;Otashu and Baldea (2018;2019;Otashu et al, 2021;Richstein and Hosseinioun, 2020;Kelley et al, 2022;Bruns et al, 2021), modifications to the design aiming to increase flexibility [Brée et al (2020;2019) propose a completely new design (Nayak-Luke et al, 2018;Fischer and Freund, 2020;Chen and Yang, 2021;Mukelabai et al, 2021;Bruns et al, 2022b;Herrmann et al, 2022;Samani et al, 2022;Semrau and Engell, 2023). All authors used modelling for simulation or optimization to study the flexibility potential, capturing the complexity of the processes with varying levels of detail, ranging from a simplified representation as a battery to dynamic process modelling.…”