Process Integration and Intensification

Martínez, Julián; Aguiar, Ana Carolina de; Machado, Ana Paula da Fonseca; Barrales, Francisco Manuel; Viganó, Juliane; Santos, Philipe dos

doi:10.1016/b978-0-08-100596-5.22819-9

Cited by 5 publications

(2 citation statements)

References 148 publications

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“…Both configurations are available in batch modes. However, probe configuration has been reported to work also with the continuous solvent flow [ 13 , 17 ]. Although less economical and more challenging to operate, probe systems are commonly preferred than batch systems due to the higher ultrasonic intensity.…”

Section: Fundamentals and Mechanismsmentioning

confidence: 99%

Low-Frequency Ultrasound Coupled with High-Pressure Technologies: Impact of Hybridized Techniques on the Recovery of Phytochemical Compounds

2021

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The coupling of innovative technologies has emerged as a smart alternative for the process intensification of bioactive compound extraction from plant matrices. In this regard, the development of hybridized techniques based on the low-frequency and high-power ultrasound and high-pressure technologies, such as supercritical fluid extraction, pressurized liquids extraction, and gas-expanded liquids extraction, can enhance the recovery yields of phytochemicals due to their different action mechanisms. Therefore, this paper reviewed and discussed the current scenario in this field where ultrasound-related technologies are coupled with high-pressure techniques. The main findings, gaps, challenges, advances in knowledge, innovations, and future perspectives were highlighted.

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Section: Fundamentals and Mechanismsmentioning

confidence: 99%

Low-Frequency Ultrasound Coupled with High-Pressure Technologies: Impact of Hybridized Techniques on the Recovery of Phytochemical Compounds

2021

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“…Using the concept of biorefinery and through the sequential integration of green extraction processes, the yield and recovery of bioactive compounds can be increased on an industrial scale, to be used as functional foods, as well as in the food, pharmaceutical and cosmetic industry [17]. However, before starting up an industrial-scale biorefinery, it is important to know all the production costs that would be associated with its implementation.…”

Section: Introductionmentioning

confidence: 99%

Production of Oil and Phenolic-Rich Extracts from Mauritia flexuosa L.f. Using Sequential Supercritical and Conventional Solvent Extraction: Experimental and Economic Evaluation

et al. 2022

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Mauritia flexuosa L.f. is a palm from the Amazon. Pulp and oil are extracted from its fruits, with a high content of bioactive compounds. This study presents the economic evaluation of two extraction processes: (a) Conventional solvent extraction (CSE) with 80% ethanol for the recovery of phenolic-rich extracts; and (b) Supercritical fluid extraction (SFE) followed by CSE to obtain oil and phenolic-rich extracts. The objective of this study was to compare the feasibility of both extraction processes. The economic evaluation and the sensitivity study were evaluated using the SuperPro Designer 9.0® software at an extraction volume of 2000 L. Similar global extraction yields were obtained for both processes; however, 8.4 and 2.4 times more total polyphenol and flavonoid content were extracted, respectively, using SFE+CSE. Cost of manufacturing (COM) was higher in SFE+CSE compared to CSE, USD 193.38/kg and USD 126.47/kg, respectively; however, in the first process, two by-products were obtained. The sensitivity study showed that the cost of the raw material was the factor that had the highest impact on COM in both extraction processes. SFE+CSE was the most economically viable process for obtaining bioactive compounds on an industrial scale from M. flexuosa L.f.

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Extraction of natural products using supercritical fluids and pressurized liquids assisted by ultrasound: Current status and trends

Dias

Aguiar

Rostagno

2021

Ultrasonics Sonochemistry

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Process Integration and Intensification

Cited by 5 publications

References 148 publications

Low-Frequency Ultrasound Coupled with High-Pressure Technologies: Impact of Hybridized Techniques on the Recovery of Phytochemical Compounds

Low-Frequency Ultrasound Coupled with High-Pressure Technologies: Impact of Hybridized Techniques on the Recovery of Phytochemical Compounds

Production of Oil and Phenolic-Rich Extracts from Mauritia flexuosa L.f. Using Sequential Supercritical and Conventional Solvent Extraction: Experimental and Economic Evaluation

Extraction of natural products using supercritical fluids and pressurized liquids assisted by ultrasound: Current status and trends

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