Producing D-Ribose from D-Xylose by Demonstrating a Pentose Izumoring Route
Jingliang Xu,
Hanyu Dong,
Song Chen
et al.
Abstract:D-Ribose plays fundamental roles in all living organisms and has been applied in food, cosmetics, health care, and pharmaceutical sectors. At present, D-ribose is predominantly produced by microbial fermentation based on the pentose phosphate pathway (PPP). However, this method suffers from a long synthetic pathway, severe growth defect of the host cell, and carbon catabolite repression (CCR). According to the Izumoring strategy, D-ribose can be produced from D-xylose through only three steps. Being not involv… Show more
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