2021
DOI: 10.3389/fbioe.2021.681253
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Production of D-Allose From D-Allulose Using Commercial Immobilized Glucose Isomerase

Abstract: Rare sugars are regarded as functional biological materials due to their potential applications as low-calorie sweeteners, antioxidants, nucleoside analogs, and immunosuppressants. D-Allose is a rare sugar that has attracted substantial attention in recent years, owing to its pharmaceutical activities, but it is still not widely available. To address this limitation, we continuously produced D-allose from D-allulose using a packed bed reactor with commercial glucose isomerase (Sweetzyme IT). The optimal condit… Show more

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Cited by 14 publications
(9 citation statements)
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“…For lower temperatures, a v max of 0.316 mmol/(g min) (55 °C, pH 7.7–7.8, 80 mM Mg 2+ ) is reported. The reaction rate for xylose is reported to be similar to those of glucose, but these reported v max values are significantly lower [0.367 μmol/(g min) and 0.316 μmol/(g min) for glucose and xylose, respectively]. This may be due to the fact that no divalent ions have been used (60 °C, pH 8.0, 0 mM X 2+ ).…”
Section: Resultsmentioning
confidence: 97%
“…For lower temperatures, a v max of 0.316 mmol/(g min) (55 °C, pH 7.7–7.8, 80 mM Mg 2+ ) is reported. The reaction rate for xylose is reported to be similar to those of glucose, but these reported v max values are significantly lower [0.367 μmol/(g min) and 0.316 μmol/(g min) for glucose and xylose, respectively]. This may be due to the fact that no divalent ions have been used (60 °C, pH 8.0, 0 mM X 2+ ).…”
Section: Resultsmentioning
confidence: 97%
“…Taken together, the IR and NMR spectroscopic and MS data were in agreement that structure 1 l represented the allose diastereoisomer of natural product 1 c. [9] The NMR spectroscopic data associated with the allose fragment within molecule 1 l was consistent with equivalent data reported for allose. [16] Furthermore, the relative configuration of natural product 1 l was secured by X-ray crystallography (Fig- ure 2B). Analysis of the absolute structure using likelihood methods, [17] was performed using PLATON.…”
Section: Resultsmentioning
confidence: 98%
“…Phenol,2-methoxy-4-(1-propenyl)-acetate is one of the synonyms of eugenol acetate. Eugenol acetate has been reported to exhibit significant antifungal, antibacterial, antiviral, and antioxidant properties. d -Allose is a rare sugar that has strong anti-inflammatory and antioxidant properties, as well as an antihypertensive agent, and can protect against ischemia-reperfusion injury of the liver . Salicin is a precursor for the synthesis of salicylic acid and shows valuable biological activities like anti-inflammatory, antitumor, and antiangiogenic .…”
Section: Discussionmentioning
confidence: 99%