Handbook of Radiopharmaceuticals 2020
DOI: 10.1002/9781119500575.ch3
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Production of Short Half‐LifePETRadionuclides

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“…The radioisotope fluorine-18 in form of anion [ 18 F]Fis produced with proton irradiation of small volume oxygen-18 enriched water targets. At the end of the bombardment, the irradiated enriched water besides [ 18 F]fluoride ion contains other radioactive as well nonradioactive ions (Kilbourn, Rodnick, and Clark, 2020). According to the European pharmacopoeia monograph, the produced fluoride-18 is purified from target water generally using anion-exchange cartridges or by electrochemical deposition and redissolution (Ph.Eur 10, 2020).…”
Section: Introductionmentioning
confidence: 99%
“…The radioisotope fluorine-18 in form of anion [ 18 F]Fis produced with proton irradiation of small volume oxygen-18 enriched water targets. At the end of the bombardment, the irradiated enriched water besides [ 18 F]fluoride ion contains other radioactive as well nonradioactive ions (Kilbourn, Rodnick, and Clark, 2020). According to the European pharmacopoeia monograph, the produced fluoride-18 is purified from target water generally using anion-exchange cartridges or by electrochemical deposition and redissolution (Ph.Eur 10, 2020).…”
Section: Introductionmentioning
confidence: 99%