Production of solid lipid microparticles loaded with lycopene by spray chilling: Structural characteristics of particles and lycopene stability

Pelissari, Julio Rafael; Souza, Volnei Brito de; Pigoso, Acácio A.; Tulini, Fabrício Luiz; Thomazini, Marcelo; Rodrigues, Christianne Elisabete da Costa; Urbano, Alexandre; Favaro-Trindade, Carmen Sílvia

doi:10.1016/j.fbp.2015.12.006

Cited by 65 publications

(49 citation statements)

References 25 publications

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“…Rocha et al (2012) reported that the stability of lycopene was improved by microencapsulation. Also, Pelissari et al (2016) showed that the microparticles loaded with lycopene by spray chilling could enhance its stability approximately 90% or more. For more bioavailability, the encapsulated bioactive ingredients should be easily released from the food, and then absorbed in the human (Shu et al, 2006;Sanz & Luyten, 2006).…”

Section: Introductionmentioning

confidence: 99%

Optimization of the conditions for producing water-in-oil-in-water microemulsions and spray-dried microcapsule of tomato extract powder

et al. 2019

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The objective of this study was to investigate optimized conditions for producing water-in-oil-in-water (W/D/W) microemulsions and spray-dried microcapsules of tomato extracts. The condition of highest yield for W/D/W microemulsification was optimized by response surface methodology (RSM). The independent variables were ratio of tomato extract to MCT (X 1 : 1:9-2:8), concentrations of emulsifier (X 2 : 0.50-1.00), and ratio of W/D to secondary aqueous coating material (X 3 : 1:5-1:9). According to the RSM results, the ratio of tomato extract to MCT at 1.24:8.76 (v/v), concentration of emulsifier at 1.00% (w/v), and ratio of W/D phase to secondary aqueous coating material of 1.00:6.16 (v/v) were found to be the optimal conditions for producing microemulsion of tomato extracts. At these conditions, the yield of W/D/W microemulsion determined as approximately 99.69%. After optimizing the conditions for producing microemulsion of tomato extract by RSM, the emulsion was spray-dried. The average particle size (D (4,3)) and zeta-potential value of the spray-dried microcapsules under optimized condition were approximately 5 µm and-29.68 mV, respectively. Results of the present study provide practical information on optimum conditions for producing W/D/W microemulsions and spray-dried microcapsules of tomato extracts.

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Section: Introductionmentioning

confidence: 99%

Optimization of the conditions for producing water-in-oil-in-water microemulsions and spray-dried microcapsule of tomato extract powder

et al. 2019

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“…A maioria dos agentes encapsulantes ou matrizes não têm todas as propriedades para ser aplicado, um revestimento adicional pode ser aplicado às micropartículas obtidas por spray chilling para garantir a completa cobertura da partícula e eliminar interações indesejáveis circundantes à mesma, durante o armazenamento e incorporação (LAKKIS, 2007 SALVIM et al, 2015, PELISSARI et al, 2016 otimização de dissolução de medicamentos pouco solúveis, modulação da liberação do composto, melhora das propriedades de fluxo, manipulação, entre outras aplicações (ILIĆ et al, 2009). …”

Section: Suplementação Da Vitamina Dunclassified

“…As partículas esféricas obtidas por spray chilling possuem boas propriedades de fluxo (ILIĆ et al, 2009). Esta característica também foi observada por diversos autores que utilizaram a técnica de spray chilling para encapsular outros materiais (MASCHKE et al, 2007;CHAMBI et al, 2008;MCCARRON;DONNELLY;AL-KASSAS, 2008;ILIĆ et al, 2009, PEDROSO et al 2012OKURO et al 2014;, SALVIM et al, 2015PELISSARI et al, 2016).…”

Section: Análise Morfológica Das Mlsunclassified

Encapsulação de colecalciferol (vitamina D3) por spray chilling

Paucar¹

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AGRADECIMENTOSAgradecer primeiramente a Deus, por estar presente em todos os momentos da minha vida, por sempre me conduzir e guiar iluminando meu caminho e pela oportunidade de poder concluir mais uma etapa da minha carreira. Além disso colocando pessoas maravilhosas na minha vida.Agradeço à minha orientadora Prof.ª Dr.ª Carmen por todos os ensinamentos, pela paciência e confiança em mim, por sempre me atender com facilidade e por todas as conversas, aconselhando-me novos caminhos a seguir e principalmente pelo grande profissional exemplar que você é, que faz de você uma pessoa maravilhosa e amada por todos. Muito obrigada.Quero agradecer a minha família (pais, irmãos) por todo o carinho, a torcida, porque mesmo de longe vocês acompanharam passo a passo mais uma etapa da minha vida, me dando conselhos e me apoiando, e isso me dá uma energia renovada.Aos amigos membros da equipe Laprof por ter tido a oportunidade de conviver com vocês ao longo dessa caminhada. Marcelo obrigado pela paciência, por todo os ensinamentos e ajuda fundamental para a realização desse mestrado. The food industry is constantly developing products that provide, in addition to nutrients, additional health benefits such as enriched food with vitamins. Vitamin D3 (cholecalciferol), which is synthesized in the skin during exposure of sunlight, controls the homeostasis of calcium and phosphorus, bone metabolism, blood pressure and renal reabsorption of calcium. The microencapsulation process has been widely applied in food and is a key objective to control the release of active agents at specific time and desired location. The spray chilling technology is interesting for microencapsulation of fat-soluble vitamins. The objective of this work was microencapsulating vitamin D3 using the spray chilling method for the production of solid lipid microparticles (SLM). For the production of the SLM it was used vegetable fat with melting point around at 48 °C as a carrier. Three treatments were established: no additives (T1), 1% of beeswax (T2), and 1% soybean lecithin (T3).The morphology of microparticles was characterized by scanning electron microscopy, laser diffraction (average size) and Fourier transform infrared spectroscopy (FTIR). Additionally, vitamin D3 stability was examined during storage at 10 and 25 °C, through periodic measurements by High-performance liquid chromatography (HLPC). The microparticles obtained were spherical with similar morphology and unimodal size distribution. The average particle size varied according to composition wherein microparticles produced with vitamin and fat were lower than other (83.0% of particles smaller than 100 μm). Spectroscopy in the infrared (FTIR) showed that there was no interaction between the components. The stability of vitamin D3 encapsulated was satisfactory over 65 days with values greater than 87% for the three treatments and temperature have any influence on the stability. The SLM produced with wax showed better stability for vitamin D3 with values of 90.18 ± 2.23% after 65 days of storage....

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“…Recentemente, esta tecnologia mostrou potencial na formação de partículas de licopeno, motivo pelo qual existe interesse no design de processos com tecnologia de CO2-SC que integrem operações de extração e formação de partículas. Com essa premissa, Blanch et al (2007) (DURANTE et al, 2016;PELISSARI et al, 2016). No caso da formação de partículas com CO2-SC, a técnica FTIR pode ser empregada no estudo de novos biomateriais carreadores para identificar grupos funcionais de caráter apolar que interagem com o CO2 (KAZARIAN et al, 1996(KAZARIAN et al, ,1997 As propriedades do carreador também influenciam nas características das partículas de licopeno.…”

Section: Estado Da Arte Da Formação De Partículas De Licopeno Com Co2unclassified

“…Na formação de partículas de licopeno já foram estudadas várias técnicas, como a secagem por pulverização (MATIOLI; RODRIGUEZ-AMAYA, 2002), pulverização a frio (PELISSARI et al 2016), pulverização eletrostática (PÉREZ-MASIÁ; LAGARON; LOPEZ-RUBIO, 2015), crioconcentração (CHIU et al, 2007), coacervacão complexa (SILVA et al, 2012), gelificação inversa (CELLI et al, 2016). Porém, a formação de partículas com morfologias adequadas não é garantia de uma proteção efetiva do pigmento no tempo considerado na avaliação da estabilidade (DURANTE et al, 2016;SILVA et al, 2012).…”

Section: Introductionunclassified

Estudo da formação de partículas de licopeno em colágeno hidrolisado usando CO2 supercrítico

Tisnado¹,

Jesús²

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Production of solid lipid microparticles loaded with lycopene by spray chilling: Structural characteristics of particles and lycopene stability

Cited by 65 publications

References 25 publications

Optimization of the conditions for producing water-in-oil-in-water microemulsions and spray-dried microcapsule of tomato extract powder

Optimization of the conditions for producing water-in-oil-in-water microemulsions and spray-dried microcapsule of tomato extract powder

Encapsulação de colecalciferol (vitamina D<sub>3</sub>) por <i>spray chilling</i>

Estudo da formação de partículas de licopeno em colágeno hidrolisado usando CO<sub>2</sub> supercrítico

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