The growth of the civil construction sector, made necessary to develop alternative products made of sustainable materials. Within this context came the cross laminated timber panels (CLT), which are formed by gluing veneer arranged at 90°, which provide high strength and great versatility, as constructive elements. This research aimed to evaluate the chemical properties of the particles of both materials and evaluate the performance of CLT panels made with Pinus oocarpa and waste wood from Coffea arabica. The panels were made with three orthogonal layers with veneer of pine and coffee wood, using the phenol-formaldehyde (PF) adhesive with a spread rate of 0.35kgm -² and the hydraulic press with a pressure of 1,2×10 7 N.m -2 for 15 min. The physical, mechanical properties, acoustic and thermal performance of the panels were evaluated. There was a significant difference for water absorption in 2 and 24 hours. The panels produced only with coffee wood waste showed the lowest water absorption rates, corresponding to 10.2 and 33.3%, in 2 and 24 hours. In relation to the MOE, the panels made with varied veneer were statistically equivalent to each other and the panels made of pine blades showed a MOE corresponding to 3,33×10 7 N.m -2 . The same trend was observed for MOR, since the average value obtained for pine panels, corresponding to 1,35x10 8 N.m -2 was significantly higher. Panels made of coffee veneer and pine veneer showed no delamination. With regard to acoustic and thermal evaluation, all panels met the minimum requirements indicated in the standards, with emphasis on coffee wood waste, associated or not with pine wood.