Production of vineomycin A1 and chaetoglobosin A by Streptomyces sp. PAL114

Aouiche, Adel; Meklat, Atika; Bijani, Christian; Zitouni, Abdelghani; Sabaou, Nasserdine; Mathieu, Florence

doi:10.1007/s13213-014-0973-1

Cited by 11 publications

(4 citation statements)

References 46 publications

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“…It is remarkable that chaetoglobosin A is known to be produced only by fungi and that this is the first report in prokaryotes. Both metabolites exhibited moderate effects against B. subtilis and Candida albicans and on filametous fungi [95].…”

Section: Antimicrobialsmentioning

confidence: 99%

Actinobacteria Derived from Algerian Ecosystems as a Prominent Source of Antimicrobial Molecules

et al. 2019

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Actinobacteria, in particular “rare actinobacteria” isolated from extreme ecosystems, remain the most inexhaustible source of novel antimicrobials, offering a chance to discover new bioactive metabolites. This is the first overview on actinobacteria isolated in Algeria since 2002 to date with the aim to present their potential in producing bioactive secondary metabolites. Twenty-nine new species and one novel genus have been isolated, mainly from the Saharan soil and palm groves, where 37.93% of the most abundant genera belong to Saccharothrix and Actinopolyspora. Several of these strains were found to produce antibiotics and antifungal metabolites, including 17 new molecules among the 50 structures reported, and some of these antibacterial metabolites have shown interesting antitumor activities. A series of approaches used to enhance the production of bioactive compounds is also presented as the manipulation of culture media by both classical methods and modeling designs through statistical strategies and the associations with diverse organisms and strains. Focusing on the Algerian natural sources of antimicrobial metabolites, this work is a representative example of the potential of a closely combined study on biology and chemistry of natural products.

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Section: Antimicrobialsmentioning

confidence: 99%

Actinobacteria Derived from Algerian Ecosystems as a Prominent Source of Antimicrobial Molecules

et al. 2019

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“…Based on morphological characteristics, 175 isolates of actinobacteria including 123 Streptomyces were purified and studied for their antimicrobial activities. After screening of all these strains, 28 of them have showed an interesting antagonistic DOI: 10.2478/arls-2021-0027 ARLS, 5,2021,[36][37][38][39][40][41][42] microbial activity. Among these isolates, the actinobacterium LG10 was isolated using chitinvitamins agar medium [7], from a sample collected from Laghouat (33°48′N, 2°52′E) in the north edge of the Algerian Sahara (Saharan Atlas).…”

Section: Isolation Of the Actinobacterial Strainmentioning

confidence: 99%

Isolation and Characterization of a New Streptomyces strain LG10 from an Unexploited Algerian Saharan Atlas

Belghit

Toumatia

Bakli

et al. 2021

Advanced Research in Life Sciences

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An actinobacterial strain named LG10 was isolated from a Saharan Atlas soil (Laghouat, Algeria). The aerial hyphae were yellowish-white on all culture media with rectiflexibiles spore chains, suggested that this bacterium attached to Streptomyces. Furthermore, LG10 contained chemical characteristics that were diagnostic for the genus Streptomyces, such as the presence of LL-diaminopimelic acid isomer (LL-DAP) and glycine amino acid. The hydrolysates of whole-cell included non-characteristic sugars. Comparative analysis of the 16S rDNA sequence displayed a similarity level of 100% with Streptomyces puniceus NRRL ISP-5058T. The antimicrobial activity of the LG10 strain was better in the culture medium MB5. Streptomyces strains are good sources of bioactive compounds with multiple biological activities.

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“…Vineomycin A1 and chaetoglobosin A reported from Streptomyces sp. PAL114 showed a strong activity especially against Candida albicans, Bacillus subtilis, and Staphylococcus aureus (Aouiche et al 2015).…”

Section: Biological Activities Of Isolated Compoundsmentioning

confidence: 99%

Bioactive-guided fractionation of diols from Streptomyces sp. MSL

et al. 2017

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An actinomycete strain with a great potential to produce bioactive compounds isolated from a laterite soil was identified as Streptomyces sp. MSL based on 16S rDNA sequence analysis. Secondary metabolites produced by the strain in optimized nutrient broth were extracted and analyzed by chromatographic and spectroscopic techniques. Among the different fractions, four diols, viz., (1) (2R,3R)-2,3-Butanediol, (2) (2R,3S)-2,3-Butanediol, (3) 2,3-dimethyl-2,3-butanediol (Pinacol), and (4) (3R)-1,3-Butanediol exhibited good antimicrobial activity. These compounds inhibited growth of both Gram-positive and Gram-negative bacteria as well as fungi tested. Minimum inhibitory concentration of these compounds was also determined against test micro-organisms in vitro. This is the first report on the occurrence of 2,3-dimethyl-2,3-butanediol (Pinacol) in the genus Streptomyces. This paper also reports the extraction, purification, and antimicrobial spectrum of diols fractionated from the culture filtrate of Streptomyces sp. MSL.

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Production of vineomycin A1 and chaetoglobosin A by Streptomyces sp. PAL114

Cited by 11 publications

References 46 publications

Actinobacteria Derived from Algerian Ecosystems as a Prominent Source of Antimicrobial Molecules

Actinobacteria Derived from Algerian Ecosystems as a Prominent Source of Antimicrobial Molecules

Isolation and Characterization of a New Streptomyces strain LG10 from an Unexploited Algerian Saharan Atlas

Bioactive-guided fractionation of diols from Streptomyces sp. MSL

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