much more (P<0.05) water than the other three groups. Meanwhile, animals fed ZTW ration showed the highest (Ρ<0.05) value of insensible water loss. The rumen fermentation indicators (pH, NH 3-N and TVFA's) were also investigated. Serum total proteins and Albumins exhibited almost similar values for the experimental groups. Animals fed treated trimming waste (YTW and ZTW) expressed higher values of Kidney function indicators (creatinine, urea, and uric acid) as compared with the other two groups (UTW and BH). The experimental diets has no effect (P<0.01) on blood concentration of total antioxidant capacity (TAC) and liver enzymes (aspartate amino transferase, alanine amino transferase, gama glutamyl transferase and alkaline phosphatase. Values of RBC's and Hb were similar in both YTW and ZTW groups compared to UTW. The values of serum immunoglobulins (IgG and IgM) in rams were higher (P<0.05) in those fed trimming waste than that fed BH. So, it can be concluded that using biologically treated trimming waste of mandarin trees could cover the nutrients required for maintenance of sheep under the desert conditions and enhanced animal immune status as well as reduction of feed cost and preventing environmental pollution.