Professional and personal impact of the COVID-19 pandemic restrictions on non-COVID-19-related clinical research

Melvin, Ann J.; Tandon, Pooja; Rowe, Carly; Clohessy, Denae S.; Palermo, Tonya M.

doi:10.1017/cts.2021.16

Cited by 6 publications

(6 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These data confirm earlier institutional and CTSA-wide surveys and are not surprising, given the widespread mandated restrictions on non-COVID-related clinical research early in the pandemic [2–4,6–8]. Additional common reasons for decreased activity reported in this and previous surveys include concerns for the safety of research participants, investigators, and staff, and staffing shortages.…”

Section: Discussionsupporting

confidence: 86%

Impact of the COVID-19 pandemic on CTSA Clinical Research Centers over 2 years

Samuels,

Hommeyer,

Booty

et al. 2023

J. Clin. Trans. Sci.

View full text Add to dashboard Cite

Introduction:The COVID-19 pandemic had an abrupt impact on patient-oriented research early in the pandemic. CTSA Clinical Research Centers (CRCs) rapidly adapted to this challenge, but the continued impact of later phases of the pandemic on CRC operations is not clear. Methods: An online REDCap survey of CTSA CRCs was developed that covered the first 2 years of the pandemic. The survey focused on impact on CRC functions, mitigation strategies, recovery of CRC activities, CRC contributions to COVID-related research, and potential lessons for future public health emergencies. The survey was sent to CRC directors at 61 CTSA Hubs in May 2022. Results: Twenty-seven Hubs (44%) responded to the survey. Most CRCs reported greater than 50% declines in inpatient census in the first year of the pandemic, with less severe impacts on outpatient census. CRCs pivoted to support COVID-related research and adopted innovative technology-driven approaches to support clinical research. Census improved in the second year of the pandemic in most CRCs but often remained below prepandemic levels, and greater than half of CRCs reported decreased revenue. Conclusions: CTSA-supported CRCs faced unprecedented challenges at the onset of the COVID-19 pandemic and responded rapidly to support COVID-related research and implement innovative approaches that allowed patient-oriented research activities to resume. However, many CRCs continued to report decreased research activities in the second year of the pandemic, and the long-term effects on CRC operations on finances are not clear. CRCs will likely need to evolve to provide support in nontraditional ways.

show abstract

Section: Discussionsupporting

confidence: 86%

Impact of the COVID-19 pandemic on CTSA Clinical Research Centers over 2 years

Samuels,

Hommeyer,

Booty

et al. 2023

J. Clin. Trans. Sci.

View full text Add to dashboard Cite

show abstract

“…Women generally carry greater responsibility in childcare than men 23 but some research has suggested that the pandemic has impacted mothers and fathers with children younger than 18 equally. 24 The pandemic may have increased the amount of time postdoctoral fellows and faculty have available for writing 7,25 but women have submitted fewer manuscripts for publication, 20,26 submitted fewer firstauthored papers, and published less than in 2019. 27 Research by the NIH indicates that extramural researchers who identify as Black or African American showed less concern about the negative impact of the pandemic on their career trajectory, were more likely to state they had organizational support, and reported no difference compared with White peers in job productivity or the impact of caretaking responsibilities on productivity.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A Mixed-Methods Analysis of Gender and Career Status Differences in the Impact of the COVID-19 Pandemic on Underrepresented Postdoctoral Fellows and Early-Career Faculty

et al. 2022

View full text Add to dashboard Cite

PurposeThe lack of racial and ethnic diversity in the biomedical workforce is pronounced and those from underrepresented backgrounds encounter more challenges than their majority counterparts. The extent of the impact of the COVID-19 pandemic on early-career investigators from underrepresented backgrounds is not yet fully understood. To examine the impact of the pandemic on underrepresented early-career biomedical researchers, this study evaluated differences in productivity, research, and psychological well-being by gender and career status. c Includes continued to work even though in close contact with people who might be infected, disruptions to work, lack of equipment or resources to work efficiently and effectively, increased workload or responsibilities, difficulties concentrating, increased financial stress, increased overall stress, and increased discrimination.

show abstract

“…While some participants found it easier to access and engage with researchers virtually, others found it difficult due to external stressors and other commitments. (Melvin et al, 2021 ) Study staff likewise needed to balance clinical and research priorities alongside home life and caretaking responsibilities exacerbated by the pandemic (Gilmartin et al, 2020 ). Furthermore, participants and researchers both experienced a learning curve adapting to virtual approaches that were sometimes novel (Loucks et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

Conducting clinical genomics research during the COVID‐19 pandemic: Lessons learned from the CSER consortium experience

Kraft

Russell

Bensen

et al. 2022

American J of Med Genetics Pt A

View full text Add to dashboard Cite

Clinical research studies have navigated many changes throughout the COVID-19 pandemic. We sought to describe the pandemic 0 s impact on research operations in the context of a clinical genomics research consortium that aimed to enroll a majority of participants from underrepresented populations. We interviewed (July to November 2020) and surveyed (May to August 2021) representatives of six projects in the Clinical Sequencing Evidence-Generating Research (CSER) consortium, which studies the implementation of genome sequencing in the clinical care of patients from populations that are underrepresented in genomics research or are medically underserved. Questions focused on COVID 0 s impact on participant recruitment, enrollment, and engagement, and the transition to teleresearch. Responses were combined and thematically analyzed. Projects described factors at the project, institutional, and community levels that affected their experiences. Project factors included the project 0 s progress at the pandemic 0 s onset, the urgency of in-person clinical care for the disease being studied, and the degree to which teleresearch procedures were already incorporated. Institutional and community factors included institutional

show abstract

Professional and personal impact of the COVID-19 pandemic restrictions on non-COVID-19-related clinical research

Abstract: This version may be subject to change during the production process.

Cited by 6 publications

References 10 publications

Impact of the COVID-19 pandemic on CTSA Clinical Research Centers over 2 years

Impact of the COVID-19 pandemic on CTSA Clinical Research Centers over 2 years

A Mixed-Methods Analysis of Gender and Career Status Differences in the Impact of the COVID-19 Pandemic on Underrepresented Postdoctoral Fellows and Early-Career Faculty

Conducting clinical genomics research during the COVID‐19 pandemic: Lessons learned from the CSER consortium experience

Contact Info

Product

Resources

About