English language learners (ELLs) are a fast-growing and diverse student population in the United States. Students with disabilities and English language learners are significant subgroups in public schools across the United States, with growing numbers on an annual basis. Educating students with disabilities and ELLs requires an advanced level of instruction to meet their unique educational needs. This chapter will identify instructional strategies to support both subgroups while keeping their educational and cultural needs at the forefront. Culturally Responsive Teaching can provide guidance for teachers to specifically meet the needs of dually identified students. Targeted suggestions for professional development were identified for novice teachers and suggestions for future research on dually identified students were provided.