Profil clinique et étiologique de l’hyperandrogénie chez la femme au CHU Mohammed VI d’Oujda

Aynaou, H.; Ongoth, F. Elilie Mawa; Latrech, H.

doi:10.1016/j.ando.2017.07.490

Cited by 1 publication

(2 citation statements)

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“…This cohort was considered small after puberty in the majority of patients (66.7%). In contrast, in the study by Aynaou et al [11] in Morocco, hirsutism appeared for the most part at puberty (58.8%). However, the onset of this symptom is more decisive than the age of onset.…”

Section: Epidemiological Characteristicsmentioning

confidence: 65%

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Profile of Female Hyperandrogenism at the Medical Clinic II: About 19 Cases

Ndour,

Diédhiou,

Sow

et al. 2023

OJEMD

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Introduction: Female hyperandrogenism is essentially manifested by hirsutism. It is present in Senegal but not yet elucidated for lack of data. This is why we proposed to study the profile of hyperandrogenism in our context. Patients and Methods: This was an observational, cross-sectional cohort study of 19 patients of reproductive age followed for hyperandrogenism at the Medical Clinic II of Abass Ndao Hospital, from November 1 st , 2019 to August 31 st , 2021. Results: Our cohort consisted of women with an average age of 25.3 years, single (73.7%), with a low socioeconomic level (42.1%). A family history of hirsutism was found in 31.6% of cases. The main reasons for consultation were a menstrual cycle disorder in 94.7% of cases, and hirsutism in 78.9% of cases. The latter was post-pubertal (66.7%), with a slow or progressive evolution. The physical examination revealed: hirsutism (100%) with an average modified Ferriman Gallwey score (mFG) of 8.9 ± 5.8, acne (36.8%), hyperseborrhea (57.9%), major signs of virilization (10.5%), acanthosis nigricans (47.4%) and galactorrhea (5.3%). Hormonal explorations revealed an elevation of: testosterone (31.6%), 17-hydroxyprogesterone (5.3%), dihydrotestosterone (31.6%), and prolactin (10.5%). The ovarian morphology was micropolycystic (84.2%). The etiological profile corresponded to polycystic ovarian syndrome or PCOS (68.4%), ovarian hyperthecosis (10.5%), hyperprolactinemia (10.5%), congenital adrenal hyperplasia or CAH (5.3%). Idiopathic hirsutism was found in 5.3% of cases. Conclusion: Female hyperandrogenism is a less frequent reason for consultation in endocrinology. It deserves to be further evaluated in a large-scale study focused on epidemiological, clinico-biological and etiological investigation, in order to assess its prevalence and better define its profile in our context.

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Section: Epidemiological Characteristicsmentioning

confidence: 65%

“…Our results are much higher than those reported by Carmina et al [12] in Italy who reported a frequency of 54.8%. In the study by Aynaou et al [11] in Morocco, cycle disorders were reported in 52.9% of cases. This can be explained by the fact that the majority of our patients seen for cycle disorders came from gynecology.…”

Section: Gynecological Historymentioning

confidence: 88%