Profil épidémiologique, clinique, histologique et thérapeutique des cancers digestifs primitifs dans les régions nord et est du Burkina Faso

Ouédraogo, S. M.; Ouedraogo, Salam; Kambire, J.L.; Zoungrana, Steve Léonce; Ouattara, Damien Z.; Bambara, Boubacar; Traoré, M.

doi:10.1016/j.bulcan.2018.09.001

Cited by 3 publications

(7 citation statements)

References 13 publications

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“…The average patient survival is significantly lower than that found in other studies in Cameroon, in particular those of Eloumou et al [12] or Bekolo et al [11] . We also note a mortality rate markedly higher than that of de Ouedraogo et al in Burkina Faso [17] but it is lower than that of Kissi Azouan-Kacou et al in Côte d'Ivoire [18] .…”

Section: Discussioncontrasting

confidence: 58%

Profile of Patients with Digestive Tube Cancer Infected With HIV in Two Cancerology Centers in Cameroon

Nga¹,

W²,

A.M³

et al. 2021

ojgh

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Background: Human Immunodeficiency Virus (HIV) infection is a major public health problem in Africa, which alone recorded 71% of HIV / AIDS-related deaths in 2018. There is a link between the infection to HIV and the occurrence of certain cancers, in particular digestive cancers. Very little data in Africa, especially Cameroon, exists on the association between HIV and digestive cancers. Our goal was to determine the prevalence of HIV in patients with cancer of the digestive tract as well as the factors related to the prognosis of these patients in Cameroon. Methods: We conducted a cross-sectional and analytical study over a 10-year period from January 2010 to December 2019. It was carried out in the general hospitals of the cities of Douala and Yaoundé. We included records of patients with histologically confirmed gastrointestinal cancer. We excluded records of patients with lymphoma or Kaposi’s sarcoma. The data collected were socio-demographic, clinical and paraclinical data. Chi-square test was used to determine statistically significant associations for p <0.05. Results: We collected 294 files, among which 71 had positive HIV serology, either a prevalence of 24.15%. The average age of the patients was 53,7±13,6 years old. The sex ratio was 1.08. The main locations were the colon with 28.7% (N = 20) and the anus with 25.4% (N = 18). At the time of HIV diagnosis, the mean CD4 count at the time of HIV diagnosis was 413,2±189,3/mm3 and the mean viral load was 5129±2786,8copies/mm3. When diagnosed with cancer, the average CD4 count was 287,84±101,7/mm3 and the average viral load was 25385,5±19784,3/mm3. The anal location (p = 0.003), the necrotic appearance (p = 0.001), the poorly differentiated character (p = 0.02) of the tumors and the death of the patients (p = 0.000) were statistically linked to positive HIV serology. Factors associated with the prognosis of HIV positive patients were CD4 count <200 / mm3 (p = 0.002) and the existence of metastases (p = 0.04) Conclusion: The prevalence of HIV in patients with cancer of the digestive tract is 24.15%. The anal location, the necrotic appearance and the undifferentiated nature of the tumors are related to positive HIV serology. Prognostic factors are a CD4 count <200 / mm3 and the existence of metastases.

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Section: Discussioncontrasting

confidence: 58%

Profile of Patients with Digestive Tube Cancer Infected With HIV in Two Cancerology Centers in Cameroon

Nga¹,

W²,

A.M³

et al. 2021

ojgh

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“…In the study by Ouedraogo S, et al [8] in Burkina Faso in 2018, the most represented socio-professional categories were farmers with 85 cases (32.6%), housewives with 81 cases (31.0%), civil servants with 55 cases (21.1%). This could explain the role of unfavorable socio-economic factors in the occurrence of these cancers.…”

Section: Discussionmentioning

confidence: 96%

“…Alcohol and tobacco are the excitants most consumed by digestive cancer patients, with proportions of 7.07% and 6.06% respectively. The study by Bagny A. et al [9] in Togo in 2015 had reported 54% smoking and 15% in that of Ouedraogo S, et al [8] in Burkina Faso in 2018.…”

Section: Discussionmentioning

confidence: 97%

“…Similar patterns have been reported by other studies such as that by Bagny A. et al [9] in Togo in 2015 had found 20% epigastralgia and 8% vomiting. Oué draogo S, et al [8] in Burkina Faso in 2018 had reported that 74% of patients had AEG.…”

Section: Discussionmentioning

confidence: 99%

“…In developed countries, the incidence of digestive cancers is declining. It is now possible to refine the description of the characteristics of these digestive cancers by specifying their molecular aspects [8]. Certain biological markers can be used to predict the efficacy of different therapeutic strategies [2].…”

Section: Introductionmentioning

confidence: 99%

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Digestive Tract Cancers: Epidemiological, Anatomical and Clinical Aspects and Management at Conakry Hospital

Sandaly,

Lansana,

Yaya

et al. 2024

CRJ

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Introduction: Digestive cancers represent between 10 and 50% of all cancers and therefore occupy a preponderant place in digestive surgery departments. Our general objective was to study the epidemiological, anatomo-clinical and therapeutic aspects of cancers of the digestive tract at the Conakry University Hospital. Methodology: This was a retrospective descriptive study covering a period of 6 years, from January 1, 2014 to December 31, 2019. Result: the hospital prevalence of cancers of the digestive tract was 6.34% with a male predominance of 54% and a sex ratio of 1.17. The average age was 52.7 years with the extremes of 13 and 84 years and 57% resided in Conakry. Alcohol and tobacco are the most popular stimulants. The most frequent reasons for consultations were epigastralgia 64.31%, vomiting / nausea 44.11%, Stomach and colon cancers were the most represented, i.e. 40.07% and 30.30% respectively. The treatment was curative (surgery) in 85.19% of cases and the outcome was favorable in almost three quarters of cases, or 71.04% of cases. We have 71 registered death cases. Conclusion: Cancers of the digestive tract remain non-negligible in our country and that of the stomach is the most common. The hope lies in equipping structures with proximity and adequate infrastructure for diagnosis and with consequent therapeutic means (radiotherapy), as well as raising awareness of early diagnosis within the community.

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Emergency Digestive Oncological Surgery in Yaounde (Cameroon): Indications and Short-Term Results

Bang¹,

Goura²,

Chopkeng³

et al. 2022

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Profil épidémiologique, clinique, histologique et thérapeutique des cancers digestifs primitifs dans les régions nord et est du Burkina Faso

Cited by 3 publications

References 13 publications

Profile of Patients with Digestive Tube Cancer Infected With HIV in Two Cancerology Centers in Cameroon

Profile of Patients with Digestive Tube Cancer Infected With HIV in Two Cancerology Centers in Cameroon

Digestive Tract Cancers: Epidemiological, Anatomical and Clinical Aspects and Management at Conakry Hospital

Emergency Digestive Oncological Surgery in Yaounde (Cameroon): Indications and Short-Term Results

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