Profile of acute ST-elevation myocardial infarction patients with hyponatremia

Devi, Konsam Biona; Chanu, Keisham Jaya; Ram, Raja; N, Narayanaswamy G; Singh, Ksh Birendra; Chongtham, Dhanaraj Singh

doi:10.4103/jms.jms_83_15

Cited by 5 publications

(7 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Of those, 10 were excluded after more detailed inspection of full texts. We finally identified 20 publications[ 13 – 32 ], including 34,782 patients, which met inclusion criteria. No additional articles were added from manual review of the references.…”

Section: Resultsmentioning

confidence: 99%

“…Baseline characteristics of 20 studies[ 13 – 32 ] included are listed in Table 1 . 8 of those are prospective cohort studies[ 13 , 14 , 18 , 21 , 23 , 24 , 26 , 32 ], others are retrospective cohort studies. The studies were conducted in the following countries: the United States, Israel, China, Indian, Korea, Poland, Czech, Denmark, Japan, Turkey, Italy and Germany.…”

Section: Resultsmentioning

confidence: 99%

“…12 studies [ 13 , 15 – 18 , 20 , 22 – 26 , 32 ] were included in the meta-analysis for the association of hyponatremia in acute coronary syndrome patients with the risk of short-term mortality, which included in-hospital mortality and all-cause mortality within 30 days. The relative risks for this association varied from 1.26 to 5.80 among 12 studies.…”

Section: Resultsmentioning

confidence: 99%

“…The underlying mechanism may be relevant to the release of vasopressin, activation of the renin-angiotensin system and catecholamine production [ 11 , 12 ]. Furthermore, previously conducted studies had reported the prevalence of hyponatremia in patients with myocardial infarction ranges from 12.5%–23.2% [ 13 ], and some correlations had found in hyponatremia and the prognosis of myocardial infarction[ 13 – 32 ]. However, those individual studies have yielded inconsistent findings, possibly caused by limitations associated with individual studies.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Short- and long-term prognostic value of hyponatremia in patients with acute coronary syndrome: A systematic review and meta-analysis

Fan

et al. 2018

PLoS ONE

View full text Add to dashboard Cite

Hyponatremia is relevant to heart failure, liver cirrhosis and stroke, but the prognostic value of serum sodium levels in patients with acute coronary syndrome are still unclear. So we did a systematic review and meta-analysis to assess the prognostic value of hyponatremia on adverse events in patients after ACS. We systematically searched PubMed, Embase and Cochrane Library to find literatures which studied the prognostic value of hyponatremia in patients with ACS. Our main endpoints were the all-cause mortality and heart failure in the short- and long-term. Of 369 identified studies, 20 studies were included in our analysis. Compared with the normal natrium, hyponatremia was significantly associated with the increased risks of all-cause mortality within 30 days (RR: 2.18; 95%CI: 1.96–2.42) and during the follow-ups (HR: 1.74; 95%CI: 1.56–1.942). For the second endpoint of short- and long-term heart failure, the pooled effect sizes in hyponatremia patients were 1.72(95%CI: 1.38–2.14) and 1.69(95%CI: 1.12–2.55) respectively. In conclusion, hyponatremia has a significant prognostic value for short- and long-term adverse event in patients after ACS, the dynamic monitoring of serum sodium levels may could help physicians to identify high risk ACS patients and to stratify risk for optimal management.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Short- and long-term prognostic value of hyponatremia in patients with acute coronary syndrome: A systematic review and meta-analysis

Fan

et al. 2018

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…24 We found significant association between hyponatraemia and anterior wall myocardial infarction with 2.9 odds of developing hyponatraemia among patients with anterior wall myocardial infarction. hyponatraemia was shown to be significantly associated with severity, progression and outcome of myocardial infarction 25 however the association between anterior wall myocardial infarction and hyponatraemia has not been completely elucidated which requires further studies to clearly find out the association.…”

Section: Discussionmentioning

confidence: 99%

Sodium Levels as a Predictor for Mortality and Morbidity in Acute Myocardial Infarction

Thomas¹,

S²

2018

jebmh

View full text Add to dashboard Cite

show abstract

A Study on the Prognostic Significance of Hyponatremia in Acute Myocardial Infarction- A Prospective Longitudinal Study

Sinha

Farooqui

Rai

2022

Global Journal for Research Analysis

View full text Add to dashboard Cite

Background: Hyponatremia, dened as a serum sodium concentration <135 mEq/L, is the most common electrolyte disorder in hospitalized patients. Hyponatremia also increases the morbidity and mortality following myocardial infarction. MI is a major cause of death and is a global health problem reaching epidemic in both developed as well as in developing countries. Aims and Objectives: To study hyponatremia as a prognostic marker in patients with acute myocardial infarction-STEMI and NSTEMI. Material and Methods: This prospective, longitudinal observational study was conducted during December 2018 – October 2020 in 152 cases of acute MI. Results: Male preponderance in the patients hospitalised due to acute MI was 73.03%. The mean age of females was 59.46±9.42 years affected by acute MI was more than males i.e. 53.23±9.92 years. Hyponatremia was present in 39.47% of the cases with acute MI. Mild hyponatremia was the most prevalent 71.67% and severe hyponatremia was the least prevalent 3.33%. Diabetes mellitus was more prevalent in cases of MI with hyponatremia 53.33% vs 25%. The GRACE scores were higher in the cases having hyponatremia and increases with the increase in severity of hyponatremia. The TIMI scores were higher in the cases having hyponatremia and increases with the increase in severity of hyponatremia. The mean duration of hospital stay was 9.99 ± 8.69 days. STEMI was more prevalent 75.66% than NSTEMI. AWMI cases were more in the population with hyponatremia 78% than in the population with normal serum sodium 53.85%. Acute MI cases with hyponatremia had lower mean LVEF than those with normal serum sodium levels. Primary reperfusion therapy (thrombolysis/primary PCI) was done in 44.08% of the cases and no signicant association was found between it and outcomes in the hyponatremia group. Complications were present in 23.03% of the cases in hyponatremia group (p <0.05). Mortality was present in 2.64% of the cases and more common in the cases with hyponatremia (p>0.05). The odds of complications (including death) was 2.91 times in the cases with hyponatremia as compared to cases with normal serum sodium levels, 2.47 times in the cases with mild hyponatremia as compared to cases with normal serum sodium levels, 3.42 times in the cases with moderate hyponatremia as compared to cases with normal serum sodium levels and 25 times in the cases severe hyponatremia as compared to cases with normal serum sodium levels. Conclusion: It can be concluded that the severity of MI is more in cases with hyponatremia and hyponatremia is associated with poorer outcomes in terms of complications post MI and mortality.

show abstract

Profile of acute ST-elevation myocardial infarction patients with hyponatremia

Cited by 5 publications

References 1 publication

Short- and long-term prognostic value of hyponatremia in patients with acute coronary syndrome: A systematic review and meta-analysis

Short- and long-term prognostic value of hyponatremia in patients with acute coronary syndrome: A systematic review and meta-analysis

Sodium Levels as a Predictor for Mortality and Morbidity in Acute Myocardial Infarction

A Study on the Prognostic Significance of Hyponatremia in Acute Myocardial Infarction- A Prospective Longitudinal Study

Contact Info

Product

Resources

About