Profile of Nodal Tuberculosis at a Tertiary Care Centre, Gwalior, India

Shrivastava, Dr Jyoti Priyadarshini; Woike, Dr Poonam; Tripathi, Dr Lokesh; Gaur, Dr Rajesh; Mangal, Dr K.S

doi:10.18535/jmscr/v3i10.44

Cited by 3 publications

(3 citation statements)

References 6 publications

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“…This is consistent with previous research, which has found that infections are a common trigger for GBS, and GI infections remain top of the list. 16,17 The study also found some differences in symptom presentation among the different GBS variants. Patients with AMAN were more likely to experience walking difficulty and symmetric ascending weakness, while patients with AIDP were more likely to experience respiratory distress and fever.…”

Section: Figure-1 Age Distribution Of Gbs Patientsmentioning

confidence: 70%

Clinical and demographic characteristics of guillain-barré syndrome (GBS) variants in a tertiary care hospital.

Haq

Samin

Durrani

et al. 2023

TPMJ

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Objective: To evaluate clinical and demographic characteristics of guillian-barre syndrome. Material & Methods: Study Design: Descriptive, Cross-sectional study. Setting: Department of Neurology, Lady Reading Hospital, Peshawar. Period: December 2020 to March 2022. Results: The study identified 117 patients with GBS, and the mean age was 43.59 ± 17.39 years. There were 78 male (67%) and 39 female (33%) patients. The most common GBS subtype was AMAN (46.2%), followed by AMSAN (34.2%), AIDP (16.2%), and atypical (2.6%). The study found a significant difference in gender distribution between the two subtypes, with male patients being more likely to have axonal GBS. Regarding antecedent events, the study found that 61% of patients had a preceding illness, with gastrointestinal infection being the most common (50%). The clinical features of GBS varied by subtype, with patients with AMAN being more likely to have walking difficulty, symmetric ascending weakness, and numbness/tingling, while patients with AIDP were more likely to have a fever and respiratory distress. Conclusion: The study's findings are broadly consistent with previous research, highlighting the heterogeneity of GBS in terms of its presentation and antecedent events. However, other differentiating points that need to be taken into consideration have also been mentioned. Furthermore, work needs to be done to raise awareness among medical professionals in Nothern Pakistan regarding the salient features of the problem.

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Section: Figure-1 Age Distribution Of Gbs Patientsmentioning

confidence: 70%

Clinical and demographic characteristics of guillain-barré syndrome (GBS) variants in a tertiary care hospital.

Haq

Samin

Durrani

et al. 2023

TPMJ

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“…This is surprising considering tubercular lymphadenitis is most common manifestation of extrapulmonary TB in children [ 7 ]. Studies from central India reported 0.4 to 22% prevalence of tubercular lymphadenitis among children (age less than 15 years) [ 36 , 37 ]. Despite the fact that these studies did not address the particular age group of under-five children but still the proportion is very low in our study especially among children with SAM.…”

Section: Discussionmentioning

confidence: 99%

Poor adherence to TB diagnosis guidelines among under-five children with severe acute malnutrition in central India: A missed window of opportunity?

2021

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Background In India, under-five children with Severe Acute Malnutrition (SAM) are referred to Nutritional Rehabilitation Centers (NRCs). NRCs screen the causes of SAM including tuberculosis (TB). The national TB programme recommends upfront testing with a rapid molecular test if TB is suspected in children. Objective We estimated the yield of and adherence to the TB diagnostic guidelines (clinical assessment and assessment for microbiological confirmation) among under-five children with SAM admitted at NRCs (six in district Sagar and four in district Sheopur) of Madhya Pradesh, India in 2017. We also explored the challenges in screening from the health care providers’ perspective. Methods It was an explanatory mixed method study. The NRC records were reviewed This was followed by three key informant interviews and three focus group discussions among staff of NRC and TB programme. Manual descriptive thematic analysis was performed. Results Of 3230, a total of 2665(83%) children underwent Mantoux test, 2438(75%) underwent physical examination, 2277(70%) were asked about the symptoms suggestive of TB, 1220(38%) underwent chest radiograph and 485(15%) were asked for recent contact with TB. A total of 547(17%) underwent assessment for microbiological confirmation. Of 547, a total of 229 gastric aspirate specimens underwent rapid molecular test (24% positive) and 318 underwent sputum microscopy (44% positive). A total of 223 were diagnosed as TB (195 microbiologically and 28 clinically confirmed) and 209 were initiated on anti-TB treatment. The treatment outcome was favourable (cure or treatment completed) for 70(31%) and not recorded for 121(54%). The main perceived challenges in screening for TB were poor team skills, lack of diagnostic facilities and poor understanding of the guidelines due to inadequate training. Conclusion Though NRCs provided a unique window of opportunity for the screening and management of TB among under-five children with SAM, the utilization of this opportunity remained suboptimal.

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“…Guillain-Barré syndrome (GBS) is an autoimmune disorder characterized by acute peripheral neuropathy (1). Although there is no precise incidence, an Indian study reports that the incidence of GBS is 48.8 to 85.2% in adults (2). According to the World Health Organisation (WHO), the annual incidence in childhood ranges from 0.6 to 4 cases per 100000.…”

Section: Introductionmentioning

confidence: 99%

Enhancing the Functional Recovery of Upper Extremities in Guillain Barre Syndrome for 10-year-Old by Combining Immersive Virtual Reality with Conventional Rehabilitation - A Unique Case Study

Vinothkumar,

Karthikeyan,

Abith Ali

2024

Int J Health Sci Res

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Background: Guillain-Barré Syndrome (GBS) is a rare autoimmune disorder affecting the peripheral nervous system, characterized by muscle weakness and pain. While conventional physiotherapy (PT) is a standard treatment, emerging technologies like immersive virtual reality (IVR) may enhance the rehabilitation outcome. Objective: This case study aimed to investigate the efficacy of combining IVR with conventional PT in the rehabilitation of a 10-year-old male diagnosed with GBS, focusing primarily on upper extremity (UE) function. Methods: The patient presented with bilateral weakness in the upper and lower extremities, along with difficulty in transitioning between positions, and reported pain in B/L UE. Conventional PT, supplemented with IVR specifically targeting UE function, was administered. Outcome measures included pain assessment using the Numerical Pain Rating Scale (NPRS), muscle power evaluation via the Medical Research Council scale (MRC), and functional independence assessed with the Functional Independence Measure (FIM). Results: Following the intervention, the patient exhibited significant improvements in pain reduction from 8/10 to 1/10, muscle power in the shoulder and elbow from 2/5 to 4/5, and wrist and finger muscles from 3/5 to 4/5. Additionally, enhancements in self-care and transfer components of FIM demonstrated increased independence in activities of daily living. Conclusion: Combining IVR with conventional PT provides a unique rehabilitation approach that enhances recovery. This approach fosters active participation, immersion, and motivation within a stimulating and enjoyable environment, which is particularly appealing for a 10-year-old patient. This case study represents the pioneering use of virtual reality in pediatric Guillain-Barré Syndrome rehabilitation, particularly in the Indian context. Key words: Guillain Baree Syndrome, Immersive Virtual Reality, Pediatric rehabilitation, Gamified exercise program.

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Profile of Nodal Tuberculosis at a Tertiary Care Centre, Gwalior, India

Abstract: Lymphadenitis is the most common extra pulmonary manifestation of tuberculosis. Tuberculous lymphadenitis is considered to be the local manifestation of the systemic disease. A high index of

Cited by 3 publications

References 6 publications

Clinical and demographic characteristics of guillain-barré syndrome (GBS) variants in a tertiary care hospital.

Clinical and demographic characteristics of guillain-barré syndrome (GBS) variants in a tertiary care hospital.

Poor adherence to TB diagnosis guidelines among under-five children with severe acute malnutrition in central India: A missed window of opportunity?

Enhancing the Functional Recovery of Upper Extremities in Guillain Barre Syndrome for 10-year-Old by Combining Immersive Virtual Reality with Conventional Rehabilitation - A Unique Case Study

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