Profile of Patients Visiting the Pediatric Emergency Service in an Egyptian University Hospital

Bazaraa, Hafez; Houchi, Salma El; Rady, Hanaa Ibrahim

doi:10.1097/pec.0b013e3182442eeb

Cited by 20 publications

(20 citation statements)

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“…Poor maternal health and low birth weight are just some of the risk factors for any type of CP. The lower social class was found to be the most common social class for the development of CP, which is in harmony with other studies in Africa; the time of brain insult during prenatal, antenatal, and acquired causes agrees with other studies [26][27][28]. Birth asphyxia was presented as the main etiological cause of CP that occurs prenatally, followed by neonatal jaundice; this is in harmony with a study done in Nigeria [29].…”

Section: Discussionsupporting

confidence: 89%

Pattern of Cerebral Palsy Among Sudanese Children Less Than 15 Years of Age

Salih

2020

Cureus

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Background: Cerebral palsy (CP) is a non-progressive, everlasting neurological disorder of movement, posture, and physical activities, with a prevalence of 2.2-3.3/1,000. CP is a condition that occurs globally, with a similar prevalence in both developed and undeveloped countries. However, the etiology differs according to the socioeconomic status of the countries. The objective is to determine the pattern and the contributing factors of CP among Sudanese children. Methods: This was a retrospective hospital-based study conducted over a period of three years in a pediatric referral hospital in Khartoum, Sudan. One hundred and eight patients of CP were enrolled, of whom 59 (54.6%) were males and 49 (45.4%) were females. Results: Spastic quadriplegic CP was the most common type. Most cases were from lower social classes. Prenatal, antenatal, and unclassified CP were found in 45 (41.7%), 31 (28.7.%), 23 (21.3%), and 9 (8.3%) cases, respectively. Birth asphyxia, neonatal jaundice, Toxoplasma gondii, rubella virus, cytomegalovirus, herpes simplex virus infections (TORCH), and sepsis (acquired) were the main causative factors. Conclusion: Spastic quadriplegia is the most common type of CP. Most of the cases had a direct positive relationship with socioeconomic status. The prenatal period was the most common period for the development of CP.

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Section: Discussionsupporting

confidence: 89%

Pattern of Cerebral Palsy Among Sudanese Children Less Than 15 Years of Age

Salih

2020

Cureus

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“…A global childhood unintentional injuries surveillance done in five major cities of LMICs suggested that falls (50.4%) and road traffic injuries (16.4%) were the most common and affect boys more often than girls (64.7% vs. 35.3%) [ 13 , 14 ]. Studies on the pediatric ED disease spectrum in developing countries show that common presenting complaints tend to be fever, upper respiratory tract infection and diarrhea [ 9 - 12 ], and common final diagnoses are upper respiratory tract infection (26.7%), viral syndrome (13.1%) and gastroenteritis (10.7%) [ 9 - 12 ]. Therefore, the majority of chief complaints and final diagnoses are infection-related (up to 64%) [ 9 - 12 ].…”

Section: Introductionmentioning

confidence: 99%

The pediatric disease spectrum in emergency departments across Pakistan: data from a pilot surveillance system

et al. 2015

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BackgroundThere is an increasing number of urgently ill and injured children being seen in emergency departments (ED) of developing countries. The pediatric disease burden in EDs across Pakistan is generally unknown. Our main objective was to determine the spectrum of disease and injury among children seen in EDs in Pakistan through a nationwide ED-based surveillance system.MethodsThrough the Pakistan National Emergency Department Surveillance (Pak-NEDS), data were collected from November 2010 to March 2011 in seven major tertiary care centers representing all provinces of Pakistan. These included five public and two private hospitals, with a collective annual census of over one million ED encounters.ResultsOf 25,052 children registered in Pak-NEDS (10% of all patients seen): 61% were male, 13% under 5 years, while almost 65% were between 10 to < 16 years. The majority (90%) were seen in public hospital EDs. About half the patients were discharged from the EDs, 9% admitted to hospitals and only 1.3% died in the EDs. Injury (39%) was the most common presenting complaint, followed by fever/malaise (19%) and gastrointestinal symptoms (18%). Injury was more likely in males vs. females (43% vs. 33%; p < 0.001), with a peak presentation in the 5-12 year age group (45%).ConclusionsPediatric patients constitute a smaller proportion among general ED users in Pakistan. Injury is the most common presenting complaint for children seen in the ED. These data will help in resource allocation for cost effective pediatric ED service delivery systems. Prospective longer duration surveillance is needed in more representative pediatric EDs across Pakistan.

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“…Additionally, in the absence of allergen, even exposure to unrelated antigens may trigger shortness of breath and wheezing, again limiting lung function and thus, seriously affecting the patients’ quality of life. Pallor is an additional well known clinical sign of severe asthma and has recently been described to occur in 10% of emergency cases [5].…”

Section: Introductionmentioning

confidence: 99%

Peripheral Erythrocytes Decrease upon Specific Respiratory Challenge with Grass Pollen Allergen in Sensitized Mice and in Human Subjects

et al. 2014

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Background and AimsSpecific hyper-responsiveness towards an allergen and non-specific airway hyperreactivity both impair quality of life in patients with respiratory allergic diseases. We aimed to investigate cellular responses following specific and non-specific airway challenges locally and systemically in i) sensitized BALB/c mice challenged with grass pollen allergen Phl p 5, and in ii) grass pollen sensitized allergic rhinitis subjects undergoing specific airway challenge in the Vienna Challenge Chamber (VCC).Methods and ResultsBALB/c mice (n = 20) were intraperitoneally immunized with grass pollen allergen Phl p 5 and afterwards aerosol challenged with either the specific allergen Phl p 5 (n = 10) or the non-specific antigen ovalbumin (OVA) (n = 10). A protocol for inducing allergic asthma as well as allergic rhinitis, according to the united airway concept, was used. Both groups of exposed mice showed significantly reduced physical activity after airway challenge. Specific airway challenge further resulted in goblet cell hyperplasia, enhanced mucous secretion, intrapulmonary leukocyte infiltration and lymphoid follicle formation, associated with significant expression of IL-4, IL-5 and IL-13 in splenocytes and also partially in lung tissue. Concerning circulating blood cell dynamics, we observed a significant drop of erythrocyte counts, hemoglobin and hematocrit levels in both mouse groups, challenged with allergen or OVA. A significant decrease in circulating erythrocytes and hematocrit levels after airway challenges with grass pollen allergen was also found in grass pollen sensitized human rhinitis subjects (n = 42) at the VCC. The effects on peripheral leukocyte counts in mice and humans however were opposed, possibly due to the different primary inflammation sites.ConclusionOur data revealed that, besides significant leukocyte dynamics, particularly erythrocytes are involved in acute hypersensitivity reactions to respiratory allergens. A rapid recruitment of erythrocytes to the lungs to compensate for hypoxia is a possible explanation for these findings.

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Profile of Patients Visiting the Pediatric Emergency Service in an Egyptian University Hospital

Abstract: Appropriate and ongoing data collection and analysis could guide more efficient utilization of pediatric emergency services to achieve better outcomes.

Cited by 20 publications

References 0 publications

Pattern of Cerebral Palsy Among Sudanese Children Less Than 15 Years of Age

Pattern of Cerebral Palsy Among Sudanese Children Less Than 15 Years of Age

The pediatric disease spectrum in emergency departments across Pakistan: data from a pilot surveillance system

Peripheral Erythrocytes Decrease upon Specific Respiratory Challenge with Grass Pollen Allergen in Sensitized Mice and in Human Subjects

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