Profiled hemodialysis reduces intradialytic symptoms

Al-Hilali, Nabieh; Al-Humoud, Hani; Ninan, V.T.; Nampoory, M.R.N.; Ali, Jafarian; Johny, K.V.

doi:10.1016/j.transproceed.2004.06.023

Cited by 16 publications

(12 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2,[12][13][14] The use of variable sodium treatment in association with the ultrafiltration profiling seems to result in a significant decline in hypotensive episodes. 15 It is possible that with the use of sodium and ultrafiltration profiling, together with adequate fluid restriction and a low-sodium diet, the adverse events registered could be even less frequent, improving patients' well-being.…”

Section: Discussionmentioning

confidence: 99%

“…Cramps showed a statistically significant decline, similar to other studies. 14,15 A step-wise model of sodium profiling was used; however, the linear model, which lowers the concentration of the sodium in the dialysate in a constant and linear way, 4 is recommended to prevent cramps. 7 There was not a significant difference in malaise and nausea and vomiting, which are common complications, in agreement with a previous study.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Influence of sodium profile in preventing complications during hemodialysis

Meira

Figueiredo

2007

Hemodialysis International

View full text Add to dashboard Cite

Although a safe procedure, hemodialysis (HD) can cause numerous complications. The objective of this study was to evaluate the incidence of complications during dialysis, interdialytic weight gain, and the predialysis and postdialysis blood pressure in HD patients with and without variable sodium. Patients were observed during 12 HD sessions and those presenting with recurrent hypotension were selected for a step-wise model of variable sodium profiling. A total of 53 patients were evaluated; the mean-SD age was 53.7+/-16.3 years and 22 (41.5%) were male. Of these, 18 (34.0%) were selected to receive variable sodium profiling: the mean (SD) age was 59.9+/-12.6 years, and 10 (55.6%) were female. A significant decline in the occurrence of cramps (p<0.027), in the mean interdialytic weight gain (p<0.009), and a tendency to reduce the number of hypotensive episodes were detected in patients using variable sodium profiling. On the other hand, predialysis systolic blood pressure presented a significant increase (p<0.048). Using variable sodium, there was a statistically significant reduction in cramps and in the mean interdialytic weight gain. There was a significant increase in predialysis systolic pressure. Regarding hypotension episodes, only a tendency toward a reduction in the frequency of hypotension episodes could be detected.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Influence of sodium profile in preventing complications during hemodialysis

Meira

Figueiredo

2007

Hemodialysis International

View full text Add to dashboard Cite

show abstract

“…File 2) [5,21,28,35,36]. A number of studies compared specific patient or treatment factors in order to establish which factor was associated with IDH, for example, interdialytic weight gain (IDWG) [20], antihypertensive medication [29], combined sodium and UF profiling [37], diabetes [9], dialysate temperature [34], and type of dialyzer used [38]. Detailed information on study design, primary research question, and use of CV medication is described in online supplementary File 2.…”

Section: Characteristics Of the Studiesmentioning

confidence: 99%

The Prevalence of Intradialytic Hypotension in Patients on Conventional Hemodialysis: A Systematic Review with Meta-Analysis

et al. 2019

View full text Add to dashboard Cite

Background: Intradialytic hypotension (IDH) is considered to be a frequent complication of hemodialysis (HD) and is associated with symptom burden, increased incidence of access failure, cardiovascular events, and higher mortality. This systematic literature review aims to analyse studies that investigated the prevalence of IDH. A complicating factor herein is that many different definitions of IDH are used in literature. Methods: A systematic literature search from databases, Medline, Cinahl, EMBASE, and the Cochrane library to identify studies reporting on the actual prevalence of IDH was conducted. Studies were categorized by the type of definition used for the prevalence of IDH. A meta-analysis of the prevalence of IDH was performed. Results: In a meta-analysis comprising 4 studies including 1,694 patients and 4 studies including 13,189 patients, the prevalence of HD sessions complicated by IDH was 10.1 and 11.6% for the European Best Practice Guideline (EBPG) definition and the Nadir <90 definition, respectively. The proportion of patients with frequent IDH could not reliably be established because of the wide range in cutoff values that were used to identify patients with frequent IDH. There was a large variety in the prevalence of symptoms and interventions. Major risk factors associated with IDH across studies were diabetes, a higher interdialytic weight gain, female gender, and lower body weight. Conclusion: Our meta-analysis suggests that the prevalence of IDH is lower than 12% for both the EBPG and the Nadir <90 definition which is much lower than stated in most reviews.

show abstract

“…About 60% of HD patients experience dizziness (Caplin, Kumar, & Davenport, 2011), which may be caused by specific factors such as drugs (Cherry, Bhardwaj, Hopps, Srour, & Pant, 2013;Lal et al, 2012), blood volume deficiency (Agarwal, Kelley, & Light, 2008), hypotension (Basri & Shaheen, 2002), anemia (Parfrey et al, 2005), malnutrition (Fortin, Bassett, & Musini, 2010), dialysis disequilibrium syndrome (Patel, Dalal, & Panesar, 2008), and inappropriate dialysate sodium concentrations (Al-Hilali et al, 2004). Healthcare professionals attempt to reduce the dizziness of HD patients by improving their nutrition, blood pressure, administering intravenous iron therapy, or adjustment of the dialysate sodium ramping for dialysis-associated dizziness (Al-Hilali et al, 2004;Fortin et al, 2010;Parfrey et al, 2005;Whitney, Wrisley, Brown, & Furman, 2004). However, these treatments could increase the risk of bacterial infections, cost, or side effect of medications (Fortin et al, 2010;Whitney et al, 2004).…”

Section: Introductionmentioning

confidence: 99%