Profiles of Dental Caries and Periodontal Disease in Individuals With or Without Psoriasis

Fadel, Hani T.; Flytström, Ingela; Calander, Ann-Marie; Bergbrant, Ing‐Marie; Heijl, Lars; Birkhed, Dowen

doi:10.1902/jop.2012.120119

Cited by 45 publications

(88 citation statements)

References 33 publications

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“…Because the NaHCO 3 cotransporter is important for the secretion of bicarbonate into the saliva, this mechanism could be a possible explanation for the observed changes in pH. Dietary induced salivary pH changes41 were minimized by abstaining from any food uptake during the investigation period.…”

Section: Discussionmentioning

confidence: 99%

Dynamic changes in saliva after acute mental stress

Naumova

Sandulescu

Bochnig

et al. 2014

Sci Rep

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Stress-related variations of fluoride concentration in supernatant saliva and salivary sediment, salivary cortisol, total protein and pH after acute mental stress were assessed. The hypothesis was that stress reactions have no influence on these parameters. Thirty-four male students were distributed into two groups: first received the stress exposure followed by the same protocol two weeks later but without stress exposure, second underwent the protocol without stress exposure followed by the stress exposure two weeks later. The stressor was a public speech followed by tooth brushing. Saliva was collected before, immediately after stress induction and immediately, at 10, 30 and 120 min. after tooth brushing. Cortisol concentrations, total protein, intraoral pH, and fluoride content in saliva were measured. The data were analyzed statistically. Salivary sediment was ca 4.33% by weight of whole unstimulated saliva. Fluoride bioavailability was higher in salivary sediment than in supernatant saliva. The weight and fluoride concentration was not altered during 2 hours after stress exposure. After a public speech, the salivary cortisol concentration significantly increased after 20 minutes compared to the baseline. The salivary protein concentration and pH also increased. Public speaking influences protein concentration and salivary pH but does not alter the fluoride concentration of saliva.

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Section: Discussionmentioning

confidence: 99%

Dynamic changes in saliva after acute mental stress

Naumova

Sandulescu

Bochnig

et al. 2014

Sci Rep

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“…However they did not adjust for other confounders such as alcohol and smoking. Another more recent case-control study by Fadel et al also found a significant difference between the mean number of remaining teeth in psoriatic and non-psoriatic patients (24 vs. 26, respectively) [25]. Our results in the context of those by Preus et al and Fadel et al, suggest that while having fewer teeth may be associated with psoriasis, it is possible that it does no precede it, as we did not find an association between fewer teeth and subsequent risk of psoriasis.…”

Section: Commentmentioning

confidence: 99%

“…The study showed that those with psoriasis had significantly lower radiographic bone level, as compared to their age- and gender-matched controls (78% vs. 17%, p < 0.001) [3]. Another more recent case-control study from Sweden, found that those with mild to moderate plaque psoriasis (89 patients) had lower radiographic alveolar bone level compared to non-psoriatics (54m patients), but after controlling for gender the association was no longer significant [25]. Interestingly, the association remained significant for males, but not females.…”

Section: Commentmentioning

confidence: 99%

Periodontal disease and risk of psoriasis among nurses in the United States

Nakib¹,

Han²,

Li³

et al. 2013

Acta Odontologica Scandinavica

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Objective Periodontal disease has been associated with systemic inflammation and may be a risk factor for autoimmune diseases. We evaluated the association between periodontal disease and the risk of incident psoriasis in a large prospective cohort study. Material and methods Self-reported history of periodontal bone loss, from 1998 to 2008, was evaluated as a risk factor for incident psoriasis among 60,457 women in the Nurses' Health Study. Secondary analyses examined associations between history of tooth loss and number of natural teeth and psoriasis risk. Cox proportional hazards models were used to assess multivariate estimates, adjusting for age, cigarette smoking, body mass index, alcohol intake and physical activity. Results We observed an increased multivariate risk of psoriasis for those with mild periodontal bone loss (RR 1.35, 95% CI: 1.03-1.75) and moderate to severe periodontal bone loss (RR 1.49, 95% CI: 1.08-2.05), as compared to those without periodontal bone loss, after adjusting for age, cigarette smoking, body mass index, alcohol intake, physical activity, and tooth loss. Number of natural teeth and tooth loss were not associated with risk of psoriasis in our study. Conclusion A history of periodontal bone loss may increase risk of subsequent psoriasis.

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“…In this sense, periodontitis and psoriasis present similar immunopathogenic process and common risk factors . Some clinical studies suggested that individuals with psoriasis have higher mean values of alveolar bone loss, increased severity of periodontal disease and higher number of missing teeth . A recent meta‐analysis evaluating 5 observational studies (cohort and case‐control studies) reported that individuals with periodontitis presented a significantly increased risk for psoriasis (pooled RR = 1.55, 95% CI: 1.35–1.77; p < 0.001).…”

Section: Introductionmentioning

confidence: 99%

“…Despite the strong rationale for this association, only few studies on this topic are available in the literature and they have shown some controversial results and limitations …”

Section: Introductionmentioning

confidence: 99%

Periodontitis as another comorbidity associated with psoriasis: A case‐control study

Mendes

Cota

Costa

et al. 2018

Journal of Periodontology

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Background The association between periodontitis and immuno‐mediated inflammatory diseases has been widely studied and recognized each more over the past few years. The aim of this study was to evaluate the potential association between psoriasis and periodontitis, as well as the influence of risk variables in this association. Methods This case‐control study included 756 individuals, 397 with psoriasis, and 359 controls. A full‐mouth periodontal examination was performed, recording therefore plaque index, probing depth, clinical attachment level, and bleeding on probing. The influence of risk variables was tested by univariate analysis and multivariate logistic regression. Results A high prevalence of periodontitis was observed among cases (46.1%) when compared to controls (33.1%). Individuals with psoriasis presented a 1.72 higher chance of having periodontitis than controls (OR = 1.72; 95% CI 1.28–2.32; p < 0.001) in the univariate analysis, but with no significance in the multivariate model. The prevalence of periodontitis increased significantly according to the severity of psoriasis [mild form (44.4%); moderate (46.3%); and advanced (47.1%)] when compared to the control group (33.1%). The final multivariate logistic model showed that the number of teeth (OR = 1.08; 95% CI 1.01–1.14; p = 0.018), smoking (OR = 1.91; 95% CI 1.19–3.07; p = 0.008), and body mass index (OR = 1.13; 95% CI 1.11–1.16; p < 0.001) remained significantly associated with the occurrence of periodontitis. Conclusions The prevalence of periodontitis was higher in individuals with psoriasis than in controls. Severity of psoriasis also presented a strong relationship with all periodontal clinical parameters.

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Profiles of Dental Caries and Periodontal Disease in Individuals With or Without Psoriasis

Cited by 45 publications

References 33 publications

Dynamic changes in saliva after acute mental stress

Dynamic changes in saliva after acute mental stress

Periodontal disease and risk of psoriasis among nurses in the United States

Periodontitis as another comorbidity associated with psoriasis: A case‐control study

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