Profitability of our lung retrieval program from non heart beating donors☆

Abstract

A total of 58.1% of preserved lungs were implanted. The ratio of obtained lungs was 11.4% of actual donors and 7.7% of total occurrences. However, this percentage could have been higher if we take into account the number of valid lungs that were not transplanted because of the lack of recipients.

An experimental study of the recovery of injured porcine lungs with prolonged normothermic cellularex vivolung perfusion following donation after circulatory death

“…What can be done prior to donation and during EVLP to mitigate the effects of prolonged donor ischemia and effects of atelectasis after transplant? Possible interventions include topical hypothermia and donor ECMO . However, many postconditioning therapies have the potential to reverse injury and further improve lung function on EVLP.…”

“…and was also described in a recent review of DCD lung donation by Erasmus et al . . Moreover, Van De Wauwer et al .…”

Assessment of lungs for transplantation: a stepwise analysis of 476 donors☆

“…On the one hand, a number of approaches have been advocated to improve the number of lung transplants performed, such as transplantation of organs with extended criteria [1], living-related donor lungs [2] and non-heartbeating donors [3]. On the other hand, there has been an effort directed towards an active medical management of potential cadaveric lung donors to ameliorate the deleterious effects of brain death on lung function.…”

Non-heart-beating donation in Spain

“…After preserving apparently suitable organs, the main reasons for not implanting them were gastric aspiration, pulmonary contusion, extrathoracic tumor, or suspected pulmonary embolism. 21 In June 2002, we performed a preclinical study to evaluate the feasibility of this program. Eight donors were assessed in terms of macroscopic appearance, functional analysis (in situ evaluation), and histological analysis to rule out edema, with excellent results.…”