Profound Hypothermia in Cardiac Surgery

Drew, C. E.; Anderson, IanM.

doi:10.1016/s0140-6736(59)91825-2

Cited by 160 publications

(33 citation statements)

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“…5,11,33,34 However, the cooling of the blood itself introduced some problems, such as the increase of blood viscosity13 and the blood cell sludging,' which induced the high gradient of temperature between core organs and peripheral tissues.…”

mentioning

confidence: 99%

Exsanguination Cooling

Ikeda

1965

Tohoku J. Exp. Med.

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mentioning

confidence: 99%

Exsanguination Cooling

Ikeda

1965

Tohoku J. Exp. Med.

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“…The Drew technique (Drew and Anderson, 1959) of inducing profound hypothermia would therefore seem too complicated and the left atrial cannulation particularly difficult. Moreover, as in Case 1, it may be thought desirable in a bad-risk patient to establish partial bypass before opening the chest, and this inevitably entails the use of an oxygenator.…”

Section: Discussionmentioning

confidence: 99%

Cardiopulmonary Bypass in Neonates

Roberts¹

1962

BMJ

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“…Both survived. 40 Profound hypothermia was a good technique in 1958 when many early oxygenators were unreliable and when operating on congenital heart disease with a competent aortic valve. It was less useful in acquired heart disease with even slight aortic regurgitation and the time limitation of one hour gave inadequate time inside the heart in complex procedures.…”

Section: Brompton Hospital á / Bubble and Film Oxygenatorsmentioning

confidence: 99%

Perfusion in Britain: the early days

Braimbridge

2004

Perfusion

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Experimental perfusion was largely the province of Germany in the nineteenth century but in the mid-twentieth century the focus of perfusion switched to the USA with the explosive clinical advances of Lillehei, Kirklin and Cooley. British clinical perfusion started with Melrose in 1953 at the Postgraduate Medical School in London but, as in other centres at that time, stopped due to the high mortality. The arrival of hands-on experience of American expertise via returning research fellows and other visitors to the USA enabled the first successful on-going series to begin at the Hammersmith Hospital with Cleland in 1957 and then to spread around the country. The various problems of those early 1950s days are described in the units starting then.

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Profound Hypothermia in Cardiac Surgery

Cited by 160 publications

References 0 publications

Exsanguination Cooling

Exsanguination Cooling

Cardiopulmonary Bypass in Neonates

Perfusion in Britain: the early days

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