Profylaktisk behandling etter varicellaeksponering

Johansen, Jeanette Schultz; Westergren, Tone; Lingaas, Egil

doi:10.4045/tidsskr.10.0149

Cited by 4 publications

(3 citation statements)

References 23 publications

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“…However, there is limited clinical evidence to support the use of antivirals for varicella prophylaxis. 37 In some patients, intravenous immunoglobulin was reportedly used as post-exposure prophylaxis to VZV; however, intravenous immunoglobulin titer levels are variable and unreliable for prophylaxis. 38 There was confusion regarding VZIG, the first commercial varicella zoster immune globulin preparation available in the United States and VARIZIG.…”

Section: Factsmentioning

confidence: 99%

Myths and Misconceptions: Varicella-Zoster Virus Exposure, Infection Risks, Complications, and Treatments

Newman

Jhaveri

2019

Clinical Therapeutics

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Varicella zoster and herpes zoster (HZ) are infections caused by the highly contagious varicella zoster virus (VZV). Despite widespread availability of vaccines against VZV, as well as varicella vaccination rates >95%, VZV remains a public health concern due to several common myths and misconceptions. Because of the success of routine varicella vaccination programs, some people mistakenly believe that varicella and HZ are now no longer a threat to public health. Another common misconception is that shingles is less infectious than varicella; however, clinical evidence demonstrates otherwise. Several knowledge gaps exist around VZV transmission and the availability and use of VARIZIG (varicella zoster immune globulin [human]) for postexposure prophylaxis against VZV. To help reduce the incidence of severe disease in high-risk individuals (eg, elderly, pregnant women, unvaccinated persons, infants, and immunocompromised children and adults), this article addresses misbeliefs and broadens awareness of VZV exposure, infection risks, complications, and treatments.

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Section: Factsmentioning

confidence: 99%

Myths and Misconceptions: Varicella-Zoster Virus Exposure, Infection Risks, Complications, and Treatments

Newman

Jhaveri

2019

Clinical Therapeutics

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“…Varicella is highly infectious and infection is both airborne and through contact (10). Localised herpes zoster is considered to be less infectious, but this may have been underestimated.…”

Section: Risk Of Infectionmentioning

confidence: 99%

“…Clinical symptoms of chickenpox may be suppressed with acyclovir, but this treatment is seldom undertaken. Prophylactic measures for selected patient groups after exposure to the varicella zoster virus have previously been discussed in the Journal of the Norwegian Medical Association (10).…”

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confidence: 99%

Varicella-zoster-virus – behov for bedre smittevern

Bjark¹,

Lingaas²

2017

Tidsskriftet

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Varicella-zoster immunoglobulin treatment in pregnant women in Denmark from 2005 to 2015: descriptive epidemiology and follow-up

2016

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Primary infection with varicella-zoster virus in pregnancy poses a risk of severe infection and embryopathies. Upon exposure, seronegative women are candidates for varicella-zoster immunoglobulin (VZIG). The aim of this paper was to describe risk factors for VZIG treatment including sources of varicella exposure and to study how many women developed clinical infection and received postpartum vaccination. We identified all pregnant women who received VZIG from December 2005 to March 2015. Additional information was obtained from Danish registers and a follow-up questionnaire. A total of 104 women were included and 88 completed the questionnaire. Significantly more women had 'other country of origin' than Denmark. They were more often second para (57%) and had most commonly been exposed to varicella by their own child (58%). Five women developed clinical varicella infection, and only 26·5% were vaccinated after delivery. The study concludes that few women developed infection after VZIG and none developed pneumonia. General practitioners should be particularly aware of obtaining varicella anamnesis in parous women from non-temperate countries in order to perform selective vaccination prior to pregnancy. In case of varicella exposure during pregnancy in a seronegative woman, postpartum vaccination is crucial.

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Profylaktisk behandling etter varicellaeksponering

Cited by 4 publications

References 23 publications

Myths and Misconceptions: Varicella-Zoster Virus Exposure, Infection Risks, Complications, and Treatments

Myths and Misconceptions: Varicella-Zoster Virus Exposure, Infection Risks, Complications, and Treatments

Varicella-zoster-virus – behov for bedre smittevern

Varicella-zoster immunoglobulin treatment in pregnant women in Denmark from 2005 to 2015: descriptive epidemiology and follow-up

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