2021
DOI: 10.2147/dddt.s338748
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Progestin-Primed Ovarian Stimulation with Clomiphene Citrate Supplementation May Be More Feasible for Young Women with Diminished Ovarian Reserve Compared with Standard Progestin-Primed Ovarian Stimulation: A Retrospective Study

Abstract: Purpose The present study was designed to compare the efficiency of the progestin-primed ovarian stimulation (PPOS) protocol with clomiphene citrate (CC) supplementation (PPOS+CC) and the standard PPOS protocol for women of different ages with diminished ovarian reserve (DOR). Patients and Methods This retrospective cohort study included 364 DOR women who underwent controlled ovarian stimulation with PPOS+CC (n = 223) or standard PPOS (n = 141). They were divided into s… Show more

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Cited by 4 publications
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“…As a result, it is possible that the suppression of pituitaryderived endogenous gonadotropins due to progestins was compensated by the stimulatory effect of clomiphene citrate. By using MPA in combination with clomiphene citrate, both the cost of treatment in OS may be reduced and patients may receive treatment for a shorter period of time [13].…”
Section: Resultsmentioning
confidence: 99%
“…As a result, it is possible that the suppression of pituitaryderived endogenous gonadotropins due to progestins was compensated by the stimulatory effect of clomiphene citrate. By using MPA in combination with clomiphene citrate, both the cost of treatment in OS may be reduced and patients may receive treatment for a shorter period of time [13].…”
Section: Resultsmentioning
confidence: 99%