1994
DOI: 10.1161/01.str.25.8.1611
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Prognosis after transient ischemic attack and ischemic stroke in young adults.

Abstract: We undertook this study to describe the risk of stroke recurrence and functional and occupational status in the long-term follow-up of young adults with ischemic strokes and to identify possible predictors for stroke recurrence, disability, and working status. A cohort of 215 patients aged < or = 45 years with ischemic cerebral events (43 transient ischemic attacks, 135 minor strokes, 37 major strokes), evaluated at our institution from May 1985 through March 1992, was followed for a mean of 43.1 … Show more

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Cited by 57 publications
(51 citation statements)
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“…Furthermore, the low prevalence of migraine and the lack of characterization of migraine subtypes in some of the previous studies prompt the speculation that several possible biases in the assessment of individual migraine history were also operant. [28][29][30][31][32][33][34][35] As an indirect support to our findings, Gioia and coworkers 36 recently found a higher prevalence of MA in young patients with stroke with silent ischemic lesions on brain MRI, an independent predictor of recurrence, in comparison with those with no evidence of brain abnormalities. This reinforces the hypothesis that MA might also predict clinical recurrent events.…”
Section: Discussionsupporting
confidence: 83%
“…Furthermore, the low prevalence of migraine and the lack of characterization of migraine subtypes in some of the previous studies prompt the speculation that several possible biases in the assessment of individual migraine history were also operant. [28][29][30][31][32][33][34][35] As an indirect support to our findings, Gioia and coworkers 36 recently found a higher prevalence of MA in young patients with stroke with silent ischemic lesions on brain MRI, an independent predictor of recurrence, in comparison with those with no evidence of brain abnormalities. This reinforces the hypothesis that MA might also predict clinical recurrent events.…”
Section: Discussionsupporting
confidence: 83%
“…3,6,15,16 The first-year mortality rates varied from 4.5% to 6.3%, 2,5-7 and the average rates were between 0.8% and 1.8% during the subsequent years. 2,[5][6][7] These figures are closely similar to ours despite the variation in the chosen upper age limit between the studies or whether patients with earlier stroke were included.…”
Section: Discussionmentioning
confidence: 99%
“…[2][3][4][5][6][7] Models for predicting outcome after stroke have been developed, 8 but because young patients typically are underrepresented in randomized trials and data sets-and because stroke characteristics between younger and older patients differ-such models may not apply to those of younger ages. Therefore, we decided to analyze death rates, causes of death, and predictors of 5-year mortality in a large, consecutive, hospital-based defined cohort of young patients with firstever ischemic stroke.…”
mentioning
confidence: 99%
“…The most important methodological limitations in most of these studies are the retrospective design, but it is not so important to evaluate the long-term consequences of stroke, since events as recurrence, death, and disability can be easyly and accurately evaluated with this methodology. The review of the clinical records (including periodic outpatient reviews) complemented with telephone interviews is the main tools for obtaining information about the patients' functional status after the stroke in the main studies about consequences of stroke in the young [9][10][11][12][13][14], including prospective series [10,11].…”
Section: Introductionmentioning
confidence: 99%