Prognosis for Fertility Analyzing Different Variables in Men and Women

Abstract

A cohort of 123 infertile couples was studied by life tables over a 30-month follow-up period to determine the influence on reproductive prognosis of clinical features, namely the women's age, previous gestational events, evolution time, and a number of conditioning infertility factors. The cumulative pregnancy rate (CPR) was 60% at 30 months. Women aged 32 years or less had a CPR of 65% and those over 32 years had a CPR of 31%. Couples with previous pregnancy had a CPR of 88%, while those with primary infertility had a CPR of 45% (marginal statistical difference). The group with infertility evolution of 36 months or less had a CPR of 75% and those with greater than 36 months infertility evolution had a CPR of 43% (p < .05). With one conditioning infertility factor a CPR of 75% was found, and with multiple factors a CPR of 47% (p < .05) was found. With these results a grading chart was created using all the analyzed criteria, determining the proportion of pregnancies per number of negative points obtained; at greater grades the proportion of pregnancy was reduced (p < .01). This report establishes the prognostic value of different variables observed in the evaluation of infertile men and women, and a simple procedure to calculate the probability to achieve pregnancy is proposed.

Factor Ovárico Endocrino

“…El pronóstico para la fertilidad en las pacientes con factor ovárico endocrino es favorable, exceptuando las pacientes con falla ovárica prematura. En un estudio de pacientes con diferentes tipos de trastornos de la fertilidad, quienes presentaron únicamente el factor ovárico endocrino comprometido tuvieron mejor pronóstico que aquellas con otros factores alterados (33) . En la Figura 2, se observa que el porcentaje acumulado de embarazo en las pacientes con factor ovárico endocrino logra su máximo de aproximadamente 80% entre 18 y 24 meses después del inicio del estudio.…”