2020
DOI: 10.21303/2504-5679.2020.001476
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Prognosis of Postoperative Progression of Glaucoma Optic Neuropathy at Primary Open-Angle Glaucoma

Abstract: Search for new informative markers and methods of prognosis prediction glaucomatous optic neuropathy (GON) in primary open-angle glaucoma (POAG) is an urgent task. We have established efficiency surgical treatment of POAG, but the progression of GON is observed in 10–15 % patients. It is known that the main mechanism of GON is apoptotic death retinal ganglion cells, a marker of which is recognized as tumour necrosis factor-α (TNFα), Fas-ligand (FasL) and a soluble form of the Fas-receptor (sFas/APO-1). T… Show more

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