Prognosis of schizophrenia spectrum disorder may not be predetermined during early development – the Northern Finland Birth Cohort 1966

Rautio, Nina; Käkelä, J.; Nordström, Tanja; Keinänen‐Kiukaanniemi, Sirkka; Ala‐Mursula, Leena; Karppinen, Jaro; Penttilä, Matti; Jääskeläinen, Erika

doi:10.1016/j.schres.2016.02.038

Schizophrenia Research

2016

DOI: 10.1016/j.schres.2016.02.038

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Prognosis of schizophrenia spectrum disorder may not be predetermined during early development – the Northern Finland Birth Cohort 1966

Nina Rautio

J. Käkelä

Tanja Nordström

et al.

Abstract: Only one of the early parenthood-related and developmental factors analysed in this study predicted outcome in individuals with SSD, while among those without SSD almost all factors were related to employment. Thus, prognosis of SSD does not seem to be predetermined much by early development.

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Cited by 4 publications

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Productivity costs of schizophrenia spectrum and other psychotic disorders by friction cost and human capital methods: The Northern Finland Birth Cohort 1966

Majuri,

Nerg,

Huikari

et al. 2024

Soc Psychiatry Psychiatr Epidemiol

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Purpose Psychotic disorders are associated with substantial productivity costs; however no previous studies have compared these between schizophrenia spectrum (SSD) and other psychotic disorders (OP). The human capital method (HCM) and the friction cost method (FCM) are the two most common approaches to assess productivity costs. The HCM focuses on employees’ perspectives on the costs, whereas the FCM demonstrates employers’ perspectives. Studies comparing these methods when estimating the productivity costs of psychoses are lacking. Methods Utilizing the Northern Finland Birth Cohort 1966 with linkages to national registers, we compared the adjusted productivity costs of SSD (n = 216) and OP (n = 217). The productivity costs were estimated from ages 18 to 53 including projections to statutory retirement age using the FCM and HCM. Results When estimated via the HCM, productivity losses were higher for SSD (€193,940) than for OP (€163,080). However, when assessed using the FCM, costs were significantly lower for SSD (€2,720) than for OP (€4,430). Productivity costs varied by sex and various clinical and occupational factors. Conclusion This study highlights how productivity costs vary by psychosis diagnosis. These differences should be noted when planning interventions. The low FCM estimates indicate the need of interventions before or during the early phases of psychoses. From a societal perspective, interventions are needed, particularly for those with highest HCM productivity losses, such as males with SSD. Besides psychiatric services, the roles of social services, employment agencies and occupational health care should be considered when helping individuals with psychoses to working life.

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Productivity costs of schizophrenia spectrum and other psychotic disorders by friction cost and human capital methods: The Northern Finland Birth Cohort 1966

Majuri,

Nerg,

Huikari

et al. 2024

Soc Psychiatry Psychiatr Epidemiol

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show abstract

Early-life factors associated with increased risk of disability pension in the national real-world schizophrenia FACE-SZ cohort study

Fond

Dubreucq²,

Verville³

et al. 2022

Eur Arch Psychiatry Clin Neurosci

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Antipsychotic-induced weight gain and birth weight in psychosis: A fetal programming model

Garriga

Fernández-Egea

Mallorquí³

et al. 2019

Journal of Psychiatric Research

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Prognosis of schizophrenia spectrum disorder may not be predetermined during early development – the Northern Finland Birth Cohort 1966

Cited by 4 publications

References 43 publications

Productivity costs of schizophrenia spectrum and other psychotic disorders by friction cost and human capital methods: The Northern Finland Birth Cohort 1966

Productivity costs of schizophrenia spectrum and other psychotic disorders by friction cost and human capital methods: The Northern Finland Birth Cohort 1966

Early-life factors associated with increased risk of disability pension in the national real-world schizophrenia FACE-SZ cohort study

Antipsychotic-induced weight gain and birth weight in psychosis: A fetal programming model

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