Prognosis of the adenocarcinoma of the cervix uteri: A comparative study

Histology as Prognostic Factor in Early-Stage Cervical Carcinoma. Experience in a Third-Level Institution

“…Although some studies support the idea that AC has a worse prognosis, one must consider that on occasion, ASC histology is included in AC 5,11,18 . To the best of our knowledge, this is the first study to compare separately the three most common histologies of CC in the early stages in Mexican women at a single institution, as most of the literature includes only SCC and AC.…”

“…Currently, CC patients with AC and adenosquamous carcinoma (ASC) histologies receive the same treatment as those with SCC 4 . However, the studies conducted have only been retrospective, and these analyzed CC prognoses according to histology in patients treated surgically or with radiotherapy (RT) [5][6][7][8][9][10][11] . Lee et al and other researchers have shown that patients with early-stage AC who are treated surgically have a very poor prognosis 8 .…”

Comparison of outcomes between squamous cell carcinoma and adenocarcinoma in patients with surgically treated stage I–II cervical cancer

“…Investigations comparing the prognosis of cervical AD with SCC came up with varying results, with certain studies reporting AD to have a poorer prognosis compared to SCC (7-11) and others reporting no statistically significant differences between the two (12)(13)(14)(15)(16). Lymph node metastasis is commonly more aggressive in AD compared to SCC and some studies reported a higher incidence of lymph node metastasis and poorer prognosis in AD compared to SCC after controlling for stage and tumor size (22)(23)(24). However, although the rates of lymph node metastasis in our AD group (19%) and SCC group (12.9%) did not differ significantly, AD was significantly associated with a worse prognosis compared to SCC in all patients.…”

Lack of any Impact of Histopathology Type on Prognosis in Patients with Early-Stage Adenocarcinoma and Squamous Cell Carcinoma of the Uterine Cervix

“…In stage IB-IIA cervical carcinoma after either radiotherapy (RT) prognosis are excellent with a 5-year overall survival ratio of 78-91 % (Landoni et al, 1997). Some reports have shown that patients with adenocarcinoma have a poorer prognosis than SCC histology (Kleine et al, 1989;Eifel et al, 1990;Hopkins and Morley, 1991;Eifel et al, 1995;Irie et al, 2000;Nakanishi et al, 2000;Xie et al, 2012;Intaraphet et al, 2013). In another study, it was reported that the recurrence rate of the pure AC group was higher than in the SCC (Lee et al, 2011).…”