Prognosis of Transient Global Amnesia: A Long-Term Follow-Up Study

Gandolfo, Carlo; Caponnetto, Claudia; Conti, Maurizio; Dagnino, N.; Sette, Massimo Del; Primavera, A.

doi:10.1159/000116787

Cited by 48 publications

(42 citation statements)

References 26 publications

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“…The present study reproduces fairly the demographic features of previous extensive studies concerning age distribution (60-to-70-year) [25][26][27][28][29][30][31] and the mean age at onset of TGA (62.67 + 9.21 years) [1,17,28,[30][31][32] There was a slight preponderance of women (sex ratio, 1.4), as already observed by others [24,25,[29][30][31][33][34][35], but this finding probably reflects the overpresentation of women among the elderly in our city. As confirmed by previous studies, the mean duration of TGA attacks was about 4 hours [5,6,18] and attacks lasting more than 12 hours were exceptional.…”

Section: Discussionsupporting

confidence: 91%

Weather conditions and transient global amnesia

et al. 2005

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Section: Discussionsupporting

confidence: 91%

Weather conditions and transient global amnesia

et al. 2005

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“…On the contrary, our findings suggest that nonfocal TNAs are not only a risk factor for stroke, but also for dementia. For 2 small subgroups of nonfocal TNAs-transient global amnesia 11,12 and dizziness 10,29 -it has been reported that the clinical course is usually more benign. Unfortunately, our data do not allow us to determine the prognosis of various subgroups of nonfocal TNAs because of small sample size.…”

Section: Commentmentioning

confidence: 99%

Incidence and Prognosis of Transient Neurological Attacks

Bos¹,

Rijn²,

Witteman³

et al. 2007

JAMA

130

142

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HE FIRST INTERNATIONALLY ACcepted clinical classification for cerebrovascular disorders was formulated in 1975. 1 It included diagnostic criteria for transient attacks of neurological dysfunction, which in the present article we will call transient neurological attacks (TNAs). The classification attempted to create a formal distinction between TNAs with an unfavorable clinical course (which were presumed to be of vaso-occlusive origin and were therefore called transient ischemic attacks [TIAs]) and more benign attacks. Transient ischemic attacks were defined as temporary attacks (commonly 2-15 minutes, maximum 24 hours) with focal symptoms, which are attributable to dysfunction of one arterial territory of the brain. The remaining TNAs, with diffuse, nonlocalizing cerebral symptoms, were considered more benign. We will call these TNAs either nonfocal TNAs, if they present with only nonfocal symptoms, or mixed TNAs, if they present with a mix of focal and nonfocal symptoms.Although the conventional diagnostic criteria for TIA are clear, it is uncertain how mixed TNAs should be classified and treated. In our experience, mixed TNAs have mostly been classified as TIAs until now, both by neurologists and by general practitioners, 2,3 but it seems reasonable to assume that some physicians may take a wait-and-see attitude in patients with mixed attacks. For nonfocal TNAs, a wide variety of diagnoses is commonly applied and none fulfills criteria for TIA. The relations between symptoms, the conventional clinical classification, and the classification used in this article follows: conventional classifies focal symptoms as TIAs and nonfocal symptoms as nonspecific, which could include syncope, confusion or transient global amnesia. The conventional classification is ambiguous on mixed symptoms. The proposed TNA classification categorizes the symp-See also p 2912 and Patient Page.

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“…A recurrence of between 2 and 15% cases has been reported, however [16]. In a case-controlled study [17], vascular risk factors carried no increased risk of TGA (n = 64).…”

Section: Pathogenesismentioning

confidence: 99%

‘Les ictus amnésiques’ and Transient Global Amnesia

Pearce

Bogousslavsky

2009

Eur Neurol

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In March 1909, R. Benon was probably the first to report a typical case of what we now call transient global amnesia. In 1956, Bender, and independently, Guyotat and Courjon described clinical and epidemiological features of transient amnesic attacks. The condition achieved general recognition after the term transient global amnesia (TGA) was introduced by Fisher and Adams in 1958. Their historic work is the main focus of this review. They reported 17 patients, with an abrupt anterograde amnesia of short duration. Classification and criteria are outlined. Various aetiologies have been postulated, but although TGA remains a clinically distinct syndrome, usually with a good prognosis, evidence of neither ischaemia nor epilepsy is demonstrable in most patients. Theories of jugular venous reflux may be relevant in some but probably not in most cases of this heterogeneous disorder.

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Prognosis of Transient Global Amnesia: A Long-Term Follow-Up Study

Cited by 48 publications

References 26 publications

Weather conditions and transient global amnesia

Weather conditions and transient global amnesia

Incidence and Prognosis of Transient Neurological Attacks

‘Les ictus amnésiques’ and Transient Global Amnesia

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