Prognostic Factors Associated with Mortality Related to Stroke in Bangui (Central African Republic)

Abstract

Stroke is a very common neurological condition that causes permanent disability in half of the cases, at least in sub-Saharan Africa. They represent the second most common cause of death in Africa. Objective of this study was to evaluate the prognostic value of the intake period of patients suffering from these conditions on the survival time of one month of hospitalization in hospitals in Bangui. We conducted a prospective study cross prognostic kind in the neurology departments, internal medicine and intensive care units of two large central hospitals from February to August 2017. Subject recruitment was complete with a made questionnaire based on the modified one of the World Health Organization on neurological disorders. A total of 154 patients were included, with a mean age of 63.15 years ± 10.98 and extremes ranging from 38 to 91 years. A male predominance was noted (60%) with a sex ratio (M/F) of 1.5. For 76 subjects (49.35%), care was taken with a hospital admission period of less than or equal to one day, while for 78 other 78 (50.65%) the admission period was higher to one day. Average admission time patients caught early was 1.00 day and the upper limit intake to one day was 4.59 ± 2.33 days with a statistically significant difference (p < 0.0001). Median admission delay for patients treated late was 4 days. Pre-hospital and hospital determinants by admission delay are presented in Table 1. The survival time was better in the group of patients who were treated early (p = 0.0039). This study shows the negative impact of late management on the survival time of patients.

Epidemiological Aspects of Stroke in Young People at the Friendship University Hospital Center in Bangui in the Central African Republic

“…This may testify to the ignorance of the population regarding this condition. This calls into question the need to carry out awareness-raising activities in order to enlighten the population in order to reduce the harmful consequences that may result from it [29].…”

30-day in-hospital stroke case fatality and significant risk factors in sub-Saharan–Africa: A systematic review and meta-analysis

“…Seventy-six studies [11,24-26,28-31, 34-37,39-48,50,52,53,55-61,63-69,71-76,78-93,96,98-104,106-108,110,111,113,114] showed low risk of bias and seventeen studies [27,33,38,37,49,51,54,62,70,77,94,95,97,105,109,112,115] showed moderate risk of bias. Twenty-two studies [26,29,32,34,39,41,46,48,50,60,61,67,68,75,76,83,85,86,92,98,110,111] had the highest overall score. One study Ukoha et al, [70] had the lowest overall score.…”

Short, Medium, and Long-Term Stroke Mortality in Libreville and Associated Factors

“…In sub-Saharan Africa, stroke is a double burden of morbidity and mortality due to a lack of appropriate infrastructure, of awareness among populations about stroke, and care that is often expensive and not accessible to all. Stroke-related mortality is poorly described in the sub-Saharan literature, the few conducted studies show high mortality rates notably, 24.04% in Burkina Faso [9], 26.8% in Cameroon [10], and 29.9% in Bangui [11] and is probably underestimated, seeing that the majority of patients in sub-Saharan Africa turn to traditional medicine [12]. In industrialized countries, however, the recourse to traditional medicine has been declining since the introduction of stroke dedicated centres known as "neurovascular units".…”

“…In industrialized countries, however, the recourse to traditional medicine has been declining since the introduction of stroke dedicated centres known as "neurovascular units". In Gabon, non-communicable diseases (NCDs) were responsible for 6,500 deaths and accounted for 21% of the risk of premature death in 2022 [11]. Essola et al (2017) found that stroke was the leading cause of medical death in the intensive care unit of Libreville University Hospital [13].…”